CAS 31477-60-8

Ormeloxifene

Description:

Ormeloxifene, also known as Centchroman, is a synthetic non-steroidal compound primarily classified as a selective estrogen receptor modulator (SERM). It is characterized by its ability to bind to estrogen receptors, exerting both estrogenic and anti-estrogenic effects depending on the target tissue. This dual action makes Ormeloxifene particularly interesting in the context of reproductive health, where it is used as an oral contraceptive and has potential applications in treating conditions like endometriosis and breast cancer. The compound is known for its relatively low side effect profile compared to traditional hormonal contraceptives, as it does not significantly affect the levels of circulating estrogen. Ormeloxifene is typically administered in a regimen that allows for its long-term use, and it has been studied for its safety and efficacy in various populations. Its chemical structure features a phenolic moiety, contributing to its biological activity, and it is often evaluated for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion.

Formula: C₃₀H₃₅NO₃

InChI: InChI=1/C30H35NO3/c1-30(2)29(23-9-5-4-6-10-23)28(26-16-15-25(32-3)21-27(26)34-30)22-11-13-24(14-12-22)33-20-19-31-17-7-8-18-31/h4-6,9-16,21,28-29H,7-8,17-20H2,1-3H3/t28-,29+/m1/s1

InChI key: InChIKey=XZEUAXYWNKYKPL-ZTMACLEXNA-N

SMILES: CC1(C)[C@@H]([C@H](C=2C(O1)=CC(OC)=CC2)C3=CC=C(OCCN4CCCC4)C=C3)C5=CC=CC=C5

Synonyms:

• 1-(2-{4-[(3R,4R)-7-methoxy-2,2-dimethyl-3-phenyl-3,4-dihydro-2H-chromen-4-yl]phenoxy}ethyl)pyrrolidine
• 1-[2-[p-(trans-7-Methoxy-2,2-dimethyl-3-phenyl-4-chromanyl)phenoxy]ethyl]pyrrolidine
• 3,4-Trans-2,2-dimethyl-3-phenyl-4-(p-(beta-pyrrolidinoethoxy)-phenyl)-7-methoxychroman
• 3,4-trans-2,2-Dimethyl-3-phenyl-4-[p-(β-pyrrolidinoethoxy)phenyl]-7-methoxychroman
• 67/20
• Brn 6075092
• Centron
• Compound 67/20
• Novex-DS
• Ormeloxifene
• Pyrrolidine, 1-(2-(4-(3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl)phenoxy)ethyl)-, trans-
• Pyrrolidine, 1-(2-(p-(7-methoxy-2,2-dimethyl-3-phenyl-4-chromanyl)phenoxy)ethyl)-, trans-
• Pyrrolidine, 1-[2-[4-[(3R,4R)-3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]-, rel-
• Saheli
• Sevista
• rel-1-[2-[4-[(3R,4R)-3,4-Dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]pyrrolidine
• trans-1-(2-(p-(7-Methoxy-2,2-dimethyl-3-phenyl-4-chromanyl)phenoxy)ethyl)pyrrolidine
• trans-2,2-Dimethyl-3-phenyl-4-(p-(beta-pyrrolidinoethoxy)phenyl)-7-methoxychroman
• trans-Centchroman
• Centchroman
• 1-[2-[p-(trans-7-Methoxy-2,2-diMethyl-3-phenyl-
• 4-chroManyl)phenoxy]ethyl]pyrrolidine
• 3,4-trans-2,2-DiMethyl-3-phenyl-4-[p-(β-
• py

Centchroman

CAS: 31477-60-8

Formula: C₃₀H₃₅NO₃

Molecular weight: 457.60

Ref: 7W-GP7469

Centchroman-d6

Controlled Product

CAS: 31477-60-8

Formula: C₃₀D₆H₂₉NO₃

Color and Shape: Neat

Molecular weight: 463.641

Ref: TR-C256602

Centchroman

Controlled Product

CAS: 31477-60-8

Formula: C₃₀H₃₅NO₃

Color and Shape: Neat

Molecular weight: 457.60

Ref: TR-C256600

Ormeloxifene

CAS: 31477-60-8

estrogen receptor modulator

Formula: C₃₀H₃₅NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 457.6

Ref: TM-T23113