CAS 315183-21-2: Procaspase activating compound 1

Description: Procaspase activating compound 1 (PAC-1) is a small molecule that plays a significant role in the activation of procaspases, which are precursors to caspases involved in the apoptotic pathway. The compound is characterized by its ability to selectively activate procaspase-3, leading to apoptosis in cancer cells, making it a potential therapeutic agent in oncology. PAC-1 is known for its relatively low molecular weight and specific structural features that facilitate its interaction with procaspases. It has been studied for its effects on various cancer cell lines, demonstrating the ability to induce cell death in a caspase-dependent manner. Additionally, PAC-1's mechanism of action involves the stabilization of procaspase-3, promoting its conversion to the active caspase-3 form. This compound is of interest in research focused on cancer treatment, particularly in the context of enhancing the efficacy of existing therapies. However, further studies are needed to fully understand its pharmacokinetics, potential side effects, and overall therapeutic potential in clinical settings.

Formula: C₂₃H₂₈N₄O₂

InChI: InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)

InChI key: InChIKey=YQNRVGJCPCNMKT-UHFFFAOYSA-N

SMILES: O=C(NN=CC1=CC=CC(=C1O)CC=C)CN2CCN(CC=3C=CC=CC3)CC2

Synonyms:

• 1-Piperazineacetic acid, 4-(phenylmethyl)-, 2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide
• 1-Piperazineacetic acid, 4-(phenylmethyl)-, [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide
• Pac-1
• Pac1
• Procaspase activating compound 1

4-(Phenylmethyl)-1-Piperazineacetic Acid-2-[[2-Hydroxy-3-(2-Allyl-1-Yl)Phenyl] Methylene] Hydrazide

CAS: 315183-21-2

• Molecular weight: 392.49g/mol

PAC-1

CAS: 315183-21-2

• Purity: ≥98%
• Molecular weight: 392.49g/mol

PAC-1

CAS: 315183-21-2

• Formula: C₂₃H₂₈N₄O₂
• Molecular weight: 392.49

PAC-1

CAS: 315183-21-2

PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, …

• Formula: C₂₃H₂₈N₄O₂
• Purity: 96.78% - 99.77%
• Color and Shape: Solid
• Molecular weight: 392.49

PAC-1

CAS: 315183-21-2

Applications PAC-1 is a caspase 3 activator. Caspase activation is a key strategy in cancer …

• Formula: C₂₃H₂₈N₄O₂
• Color and Shape: Neat
• Molecular weight: 392.49

PAC 1

CAS: 315183-21-2

Please enquire for more information about PAC 1 including the price, delivery time and more …

• Formula: C₂₃H₂₈N₄O₂
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 392.49 g/mol