CAS 31542-63-9

1,3-Dipropyl-7-methylxanthine

Description:

1,3-Dipropyl-7-methylxanthine, with the CAS number 31542-63-9, is a xanthine derivative that exhibits properties similar to caffeine and theobromine. This compound is characterized by its structure, which includes a xanthine core with two propyl groups at the 1 and 3 positions and a methyl group at the 7 position. It is known for its role as a selective antagonist of adenosine receptors, particularly A1 and A2A subtypes, which can influence various physiological processes, including neurotransmission and cardiovascular function. The compound is typically studied for its potential effects on cognitive function and its use in pharmacological research. In terms of solubility, it is generally soluble in organic solvents but may have limited solubility in water. Its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are of interest in the context of its biological activity. Overall, 1,3-Dipropyl-7-methylxanthine serves as a valuable tool in understanding adenosine receptor modulation and its implications in various health conditions.

Formula: C₁₂H₁₈N₄O₂

InChI: InChI=1S/C12H18N4O2/c1-4-6-15-10-9(14(3)8-13-10)11(17)16(7-5-2)12(15)18/h8H,4-7H2,1-3H3

InChI key: InChIKey=QVAYTZAGDQIWMB-UHFFFAOYSA-N

SMILES: C(CC)N1C2=C(C(=O)N(CCC)C1=O)N(C)C=N2

Synonyms:

• 1,3-Dipropylheteroxanthine
• 1H-Purine-2,6-dione, 3,7-dihydro-7-methyl-1,3-dipropyl-
• 3,7-Dihydro-7-methyl-1,3-dipropyl-1H-purine-2,6-dione
• 7-Methyl-1,3-dipropylxanthine
• 7-methyl-1,3-dipropyl-3,7-dihydro-1H-purine-2,6-dione
• Heteroxanthine, 1,3-dipropyl-
• Sc 5192
• (1,3)-Dipropyl-7-methylxanthine

7-Methyl-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione

CAS: 31542-63-9

Formula: C₁₂H₁₈N₄O₂

Color and Shape: Solid

Molecular weight: 250.2969

Ref: IN-DA00BXBR

1,3-Dipropyl-7-methylxanthine

CAS: 31542-63-9

Formula: C₁₂H₁₈N₄O₂

Molecular weight: 250.30

Ref: 7W-GL5491

1,3-Dipropyl-7-methylxanthine

Controlled Product

CAS: 31542-63-9

Applications A phosphodiesterase inhibitor and caffeine analog with some selectivity for A2 adenosine receptors. UV lmax = 273 nm, log e=3.98.
References Clark, K., et al.: J. Physiol., 481, 129 (1994), Liu, W., et al.: Pharmacol., 54, 135 (1997), Zarrindast, M., et al.: Eur. Neuropsychopharmacol., 13, 165 (2003), Malki, A., et al.: Exp. Oncol., 28, 16 (2006),

Formula: C₁₂H₁₈N₄O₂

Color and Shape: Neat

Molecular weight: 250.30

Ref: TR-D492400

1,3-Dipropyl-7-methylxanthine

Controlled Product

CAS: 31542-63-9

1,3-Dipropyl-7-methylxanthine is a xanthine compound that is structurally related to caffeine. It has been shown to have an inhibitory effect on the production of reactive oxygen species and cytosolic calcium levels in primary cells, as well as a nonselective adenosine receptor antagonist activity. It has also been shown to antagonize the effects of adenosine receptors, p2 receptors, and p2y receptors. This drug is used for the treatment of basophilic leukemia.

Formula: C₁₂H₁₈N₄O₂

Purity: Min. 95%

Molecular weight: 250.3 g/mol

Ref: 3D-FD22522