CAS 31556-28-2

1-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-beta-D-ribofuranosyl]-4-thioxo-3,4-dihydropyrimidin-2(1H)-one

Description:

The chemical substance known as 1-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-beta-D-ribofuranosyl]-4-thioxo-3,4-dihydropyrimidin-2(1H)-one, with the CAS number 31556-28-2, is a complex organic compound characterized by its unique structural features. It contains a ribofuranosyl sugar moiety, which is indicative of its potential biological activity, particularly in nucleic acid chemistry. The presence of multiple phosphoryl groups suggests that it may play a role in biochemical pathways involving phosphorylation, which is crucial for cellular signaling and energy transfer. Additionally, the thioxo group contributes to its reactivity and may influence its interaction with biological targets. This compound is likely to exhibit properties associated with nucleoside analogs, potentially impacting its use in therapeutic applications, such as antiviral or anticancer treatments. Its intricate structure and functional groups make it a subject of interest in medicinal chemistry and biochemistry, warranting further investigation into its biological effects and mechanisms of action.

Formula: C₉H₁₅N₂O₁₄P₃S

InChI: InChI=1/C9H15N2O14P3S/c12-6-4(3-22-27(18,19)25-28(20,21)24-26(15,16)17)23-8(7(6)13)11-2-1-5(29)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,10,14,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1

SMILES: c1cn([C@H]2[C@@H]([C@@H]([C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)O)O)c(=O)nc1S

Synonyms:

• 4-Thiouridine-5'-triphosphate sodium salt
• Uridine 5'-(tetrahydrogen triphosphate), 4-thio-
• 4-thiouridine triphosphate

4-Thiouridine-5'-triphosphate sodium salt - aqueous solution

CAS: 31556-28-2

4-Thiouridine-5'-triphosphate sodium salt - aqueous solution (4TUTP) is an analog of uridine and can be used as a template for the synthesis of single-stranded DNA. 4TUTP has been shown to have a high affinity for dsDNA, allowing it to form a ternary complex with DNA polymerase and single-stranded DNA template. 4TUTP can also be used to prepare samples for profiling experiments or other molecular studies. It is reactive, so should be handled with caution in order to avoid unwanted crosslinking. 4TUTP may also be used in chloroplast research.

Formula: C₉H₁₅N₂O₁₄P₃S·xNa

Purity: Min. 95 Area-%

Color and Shape: Clear Liquid

Molecular weight: 500.20 g/mol

Ref: 3D-NT34810