CAS 31556-75-9

Monamycin B1 (8CI,9CI)

Description:

Monamycin B1, with the CAS number 31556-75-9, is a naturally occurring antibiotic that belongs to the class of compounds known as aminoglycosides. It is produced by certain strains of the bacterium Micromonospora. This compound exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria, making it of interest in pharmaceutical applications. Monamycin B1 is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. The compound is known for its ability to inhibit protein synthesis in bacteria, thereby preventing their growth and replication. Additionally, Monamycin B1 has been studied for its potential use in treating various infections, although its clinical application may be limited due to resistance issues and toxicity concerns associated with aminoglycosides. Overall, Monamycin B1 represents a significant area of research in antibiotic development, highlighting the ongoing need for effective antimicrobial agents in the face of rising antibiotic resistance.

Formula: C₃₃H₅₅N₇O₈

Synonyms:

• N-[1-[N-[[2-[[D-Hexahydro-2-(L-2-hydroxy-3-methyl-1-oxobutyl)-3-pyridazinyl]carbonyl]-L-hexahydro-cis-5-hydroxy-3-pyridazinyl]carbonyl]-N-methyl-D-leucyl]-trans-4-methyl-L-prolyl]-D-valinep-lactone
• D-Valine, N-[1-[N-[[2-[[D-hexahydro-2-(L-2-hydroxy-3-methyl-1-oxobutyl)-3-pyridazinyl]carbonyl]-L-hexahydro-cis-5-hydroxy-3-pyridazinyl]carbonyl]-N-methyl-D-leucyl]-trans-4-methyl-L-prolyl]-,p-lactone
• 2H-Dipyridazino[1,6-d:1',6'-g]pyrrolo[1,2-m][1,4,7,10,13,16]oxapentaazacyclooctadecine,cyclic peptide deriv.

Monamycin B

CAS: 31556-75-9

Monamycin B is an ester peptide antibiotic with activity against Gram-positive bacteria.

Formula: C₃₃H₅₅N₇O₈

Color and Shape: Solid

Molecular weight: 677.83

Ref: TM-TN11004