
CAS 31557-15-0
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((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
CAS:Controlled Product<p>Applications ((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.<br>References Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Formula:C7H17ClOSiColor and Shape:NeatMolecular weight:180.75
