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CAS 31576-00-8

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(+)-Oxprenolol

Description:
(+)-Oxprenolol is a beta-adrenergic antagonist, commonly known as a beta-blocker, primarily used in the treatment of hypertension and certain heart conditions. It exhibits both selective and non-selective properties, meaning it can block beta-1 and beta-2 adrenergic receptors, which are involved in the regulation of heart rate and vascular tone. The substance is characterized by its ability to reduce heart rate, decrease myocardial contractility, and lower blood pressure, making it effective in managing cardiovascular diseases. Chemically, (+)-Oxprenolol is a racemic mixture, but the (+) enantiomer is the active form responsible for its therapeutic effects. It is typically administered orally and has a moderate bioavailability. The compound is also known for its lipophilicity, allowing it to cross biological membranes effectively. Side effects may include fatigue, dizziness, and gastrointestinal disturbances, and it should be used with caution in patients with respiratory conditions due to its potential to induce bronchospasm. Overall, (+)-Oxprenolol plays a significant role in cardiovascular pharmacotherapy.
Formula:C15H23NO3
InChI:InChI=1S/C15H23NO3/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3/h4-8,12-13,16-17H,1,9-11H2,2-3H3/t13-/m1/s1
InChI key:InChIKey=CEMAWMOMDPGJMB-CYBMUJFWSA-N
SMILES:O(C[C@@H](CNC(C)C)O)C1=C(OCC=C)C=CC=C1
Synonyms:
  • (2R)-1-(propan-2-ylamino)-3-[2-(prop-2-en-1-yloxy)phenoxy]propan-2-ol
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-, (2R)-
  • (R)-1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol
  • (2R)-1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-2-propanol
  • 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-, (+)-
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-, (R)-
  • Oxyprenolol
  • 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-, (2R)-
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