CAS 31592-08-2

[1,2,4]Triazolo[1,5-a]pyrimidin-7(1H)-one

Description:

[1,2,4]Triazolo[1,5-a]pyrimidin-7(1H)-one is a heterocyclic compound characterized by a fused triazole and pyrimidine ring system. This compound features a triazole ring, which consists of three nitrogen atoms and two carbon atoms, fused to a pyrimidine ring that contains two nitrogen atoms and four carbon atoms. The presence of the carbonyl group at the 7-position contributes to its reactivity and potential biological activity. It is often studied for its pharmacological properties, including potential applications in medicinal chemistry as an antitumor or antiviral agent. The compound is typically solid at room temperature and may exhibit moderate solubility in polar solvents. Its structure allows for various substitutions, which can influence its chemical behavior and biological activity. As with many heterocycles, it may participate in various chemical reactions, including nucleophilic substitutions and cycloadditions, making it a versatile building block in organic synthesis. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₅H₄N₄O

1H,7H-[1,2,4]Triazolo[1,5-a]pyrimidin-7-one

CAS: 31592-08-2

Fluconazole is an oral antifungal drug that is used to treat a variety of fungal infections such as candida, cryptococcus, and histoplasmosis. It binds to the 14-alpha-demethylase enzyme in the fungal cell membrane and inhibits the synthesis of ergosterol, which is an essential component of the cell membrane. This prevents the formation of ergosterol crystals that are necessary for maintaining cell shape and function. Fluconazole has been shown to be effective against influenza virus and other viruses that use subunits similar to those found in fluconazole. Fluconazole also has antibacterial properties against bacteria such as Staphylococcus aureus and Streptococcus pneumonia. The pharmacokinetic properties of fluconazole have been studied using ethyl bromoacetate and carboxylate derivatives. Fluconazole has also been shown to inhibit methicillin-resistant Staphylococcus

Formula: C₅H₄N₄O

Purity: Min. 95%

Molecular weight: 136.11 g/mol

Ref: 3D-GBA59208