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CAS 316-81-4

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Thioproperazine

Description:
Thioproperazine is an antipsychotic medication belonging to the phenothiazine class, primarily used to treat various psychiatric disorders, including schizophrenia and severe anxiety. It functions as a dopamine antagonist, primarily blocking D2 receptors in the brain, which helps alleviate symptoms of psychosis. The chemical formula of thioproperazine is C19H22N2S, and it features a thiazine ring, which is characteristic of phenothiazines. This compound is typically administered in its hydrochloride salt form for better solubility and bioavailability. In addition to its antipsychotic properties, thioproperazine may also exhibit antiemetic effects, making it useful in managing nausea and vomiting. Common side effects can include sedation, weight gain, and extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its pharmacological profile, thioproperazine requires careful monitoring for potential adverse effects, particularly in long-term use. As with any medication, it is essential to use thioproperazine under the guidance of a qualified healthcare professional.
Formula:C22H30N4O2S2
InChI:InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3
InChI key:InChIKey=VZYCZNZBPPHOFY-UHFFFAOYSA-N
SMILES:C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3
Synonyms:
  • 7843Rp
  • Cephalmin
  • N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide
  • N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-2-phenothiazinesulfonamide
  • Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-
  • Rp 7843
  • Skf 5883
  • Sulfenazin
  • Thioperazine
  • Thioproperazin
  • See more synonyms
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