CAS 31645-12-2

4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo-, sodium salt (1:1)

Description:

4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo-, sodium salt (1:1), commonly referred to as sodium thioxo-uracil, is a chemical compound characterized by its pyrimidine ring structure, which is a six-membered aromatic ring containing nitrogen atoms. This compound features a thioxo group, contributing to its reactivity and potential biological activity. As a sodium salt, it is typically soluble in water, which enhances its utility in various applications, including pharmaceuticals and biochemistry. The presence of the thioxo group may impart unique properties, such as antioxidant activity or the ability to interact with biological macromolecules. This compound is often studied for its potential therapeutic effects, particularly in the context of cancer research and antiviral applications. Its molecular structure allows for various interactions, making it a subject of interest in medicinal chemistry. Safety and handling precautions should be observed, as with any chemical substance, to mitigate potential hazards associated with its use.

Formula: C₄H₄N₂O₂S·Na

InChI: InChI=1S/C4H4N2O2S.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);

InChI key: InChIKey=LHWPSDLHLAAELL-UHFFFAOYSA-N

SMILES: O=C1CC(=O)NC(=S)N1.[Na]

Synonyms:

• 2-Thiobarbituric acid sodium
• 4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo-, sodium salt (1:1)
• 4,6(1H,5H)-pyrimidinedione, dihydro-2-thioxo-, monosodium salt
• 4,6-Dihydroxy-2-Mercaptopyrimidine Sodium Salt
• 6(1H,5H)-Pyrimidinedione,Dihydro-2-Thioxo-Monosodiumsalt
• Barbituric acid, 2-thio-, monosodium salt
• Na-Tba
• Sodium 2-Thiobarbiturate
• Sodium 6-Oxo-2-Thioxo-1,2,5,6-Tetrahydropyrimidin-4-Olate
• Sodium Thiobarbituric Acid
• Sodium thiobarbiturate

2-Thiobarbituric Acid Sodium Salt

CAS: 31645-12-2

Formula: C₄H₃N₂NaO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.1336

Ref: IN-DA003HY2

Sodium 2-Thiobarbiturate

CAS: 31645-12-2

Formula: C₄H₃N₂NaO₂S

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 166.13

Ref: 3B-T0193

Sodium 2-thiobarbiturate

Controlled Product

CAS: 31645-12-2

Sodium 2-thiobarbiturate is a nitrosating agent that has been shown to protect the lungs from ischemia–reperfusion injury in vitro. It exerts its protective effects by inhibiting the release of nitric oxide (NO) and protects against neuronal death by preventing mitochondrial dysfunction. Sodium 2-thiobarbiturate also has genotoxic effects, which are reduced in the presence of antioxidants, and can cause DNA damage. This drug is reactive with oxygen, so it should not be stored in airtight containers or exposed to light.

Formula: C₄H₄N₂O₂S·Na

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 167.14 g/mol

Ref: 3D-FS166860