CAS 31690-09-2

L-Methylfolate

Description:

L-Methylfolate, with the CAS number 31690-09-2, is the biologically active form of folate, a B-vitamin (B9) that plays a crucial role in various physiological processes. It is essential for DNA synthesis, repair, and methylation, as well as for the production of red blood cells. L-Methylfolate is particularly important in the metabolism of homocysteine, an amino acid linked to cardiovascular health. This compound is water-soluble and typically exists as a white to pale yellow crystalline powder. It is stable under normal conditions but can be sensitive to light and heat. L-Methylfolate is often used in dietary supplements and fortification due to its enhanced bioavailability compared to other forms of folate, such as folic acid. It is particularly beneficial for individuals with certain genetic polymorphisms that impair the conversion of folic acid to its active form. Additionally, L-Methylfolate has been studied for its potential therapeutic effects in mood disorders and other health conditions, highlighting its significance in both nutrition and medicine.

Formula: C₂₀H₂₅N₇O₆

InChI: InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1

InChI key: InChIKey=ZNOVTXRBGFNYRX-STQMWFEESA-N

SMILES: CN1C2=C(NC[C@@H]1CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)NC(N)=NC2=O

Synonyms:

• L-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, (S)-
• L-Glutamic acid, N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-
• N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid
• L-Glutamic acid, N-[4-[[[(6S)-2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-
• Glutamic acid, N-[p-[[(2-amino-5,6,7,8-tetrahydro-4-hydroxy-5-methyl-6-pteridinyl)methyl]amino]benzoyl]-, L-(-)-

Levomefolic Acid

CAS: 31690-09-2

Formula: C₂₀H₂₅N₇O₆

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 459.46

Ref: 3B-L0335

(S)-N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

CAS: 31690-09-2

Formula: C₂₀H₂₅N₇O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 459.4558

Ref: IN-DA0039B6

Levomefolic Acid

CAS: 31690-09-2

Levomefolic Acid

Purity: ≥95%

Molecular weight: 459.46g/mol

Ref: 54-BUP14491

Levomefolic Acid

CAS: 31690-09-2

Levomefolic Acid

Purity: 98%

Molecular weight: 459.46g/mol

Ref: 54-OR1030497

Levomefolic Acid (L-5-Methyltetrahydrofolic Acid)

CAS: 31690-09-2

Formula: C₂₀H₂₅N₇O₆

Molecular weight: 459.47

Ref: 4Z-L-382

Levomefolic Acid

CAS: 31690-09-2

Levomefolic Acid (5-MTHF) is a natural, active form of folic acid used at the cellular level for DNA reproduction and the cysteine cycle among other functions.

Formula: C₂₀H₂₅N₇O₆

Purity: 97.27%

Color and Shape: Solid

Molecular weight: 459.46

Ref: TM-T7094

Levomefolic Acid

CAS: 31690-09-2

Applications A natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid. It has been proposed for treatment of cardiovascular disease.
References Willems, F. et al.: Br. J. Pharmacol., 145, 823 (2004); Prinz-Langhebohi, R.: et al., Br. J. Pharmacol., 158, 2014 (2009); Wright, A. et al.: Brit, J. Nutrit., 103, 724 (2010)

Formula: C₂₀H₂₅N₇O₆

Color and Shape: Neat

Molecular weight: 459.46

Ref: TR-L375730

Levomefolic acid

CAS: 31690-09-2

Levomefolic acid is a derivative of folic acid and belongs to the group of dinucleotide phosphates. It has been shown to have a protective effect against blood clots, and is used in the treatment of pernicious anaemia, megaloblastic anaemia, and leukopenia. Levomefolic acid also inhibits energy metabolism in bacteria. Its mode of action is not fully understood but it has been demonstrated that it inhibits enzyme activities such as methylenetetrahydrofolate reductase (MTHFR) and 5-methyltetrahydrofolate cyclohydrolase. The production of DNA nucleotides has also been shown to be inhibited by the drug. Levomefolic acid has also been shown to have an effect on redox potentials in cancer cell lines. In addition, it has been found that levomefolic acid can be transferred from maternal blood to human serum.

Formula: C₂₀H₂₅N₇O₆

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 459.46 g/mol

Ref: 3D-FL24884