CAS 317-34-0: Aminophylline
Description:Aminophylline is a pharmaceutical compound that is a combination of theophylline and ethylenediamine. It is primarily used as a bronchodilator to treat respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). The substance acts by relaxing the muscles of the airways, thereby improving airflow and alleviating symptoms of bronchospasm. Aminophylline is typically administered intravenously or orally, depending on the clinical situation. It has a relatively low solubility in water, which can affect its absorption and bioavailability. The compound exhibits a range of pharmacological effects, including anti-inflammatory properties and the ability to enhance respiratory muscle function. Its mechanism of action involves the inhibition of phosphodiesterase, leading to increased levels of cyclic AMP, which promotes bronchodilation. However, it is important to monitor its use due to potential side effects, such as gastrointestinal disturbances, cardiovascular effects, and central nervous system stimulation. Overall, aminophylline remains a valuable therapeutic agent in managing airway diseases, although its use must be carefully managed to avoid toxicity.
Formula:C7H8N4O2C2H8N2
InChI:InChI=1S/C7H8N4O2.C2H8N2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4/h3H,1-2H3,(H,8,9);1-4H2
InChI key:InChIKey=LHRHXWBJUQKYEL-UHFFFAOYSA-N
SMILES:O=C1C=2NC=NC2N(C(=O)N1C)C.NCCN
- Synonyms:
- 1,2-Ethanediamine, compd. with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:2)
- 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - ethane-1,2-diamine (1:1)
- 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - ethane-1,2-diamine (2:1)
- 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - ethane-1,2-diamine hydrate (2:1:1)
- 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1)
- 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compound with 1,2-ethanediamine (2:1)
- 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-, compd. with 1,2-ethanediamine (2:1)
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione comp. with 1,2-ethanediamine (2:1)
- Aminocardol
- Aminodur
- See more synonyms
- Aminofilina
- Aminophyllin
- Aminophyllin Hydrate
- Aminophylline anhydrous
- Aminophylline hydrate
- Ammophyllin
- Cardiofilina
- Cardiomin
- Cardophylin
- Cardophyllin
- Carena
- Carine
- Cidophylline
- Diaphylline
- Diophllin
- Diophyllin
- Diuxanthine
- Dobo
- Dura-Tab S.M. Aminophylline
- Ethophylline
- Ethylenediamine, compd. with theophylline (1:2)
- Euphyllin
- Euphyllin CR
- Euphyllin CR N 300
- Euphylline
- Eurphyllin
- Euufillin
- Genophyllin
- Grifomin
- Inophylline
- Lasodex
- Linampheta
- Metaphyllin
- Metaphylline
- Methophylline
- Minaphil
- Minaphol
- Miofilin
- Neophyiline
- Norofilina
- Novophyllin
- Novphyllin
- Pecram
- Peterphyllin
- Phylcardin
- Phyllindon
- Phyllocontin
- Pylcardin
- Rectalad-aminophylline
- Somophyllin
- Somophyllin O
- Stenovasan
- Syntophyllin
- Tefamin
- Teofyllamin
- Theodrox
- Theolamine
- Theolone
- Theomin
- Theophyldine
- Theophyllamine
- Theophyllaminum
- Theophylline compd. with ethylenediamine
- Theophylline, compd. with ethylenediamine (2:1)
- Theophylline, compound with ethylenediamine (2 to 1) dihydrate
- Theophylline--Ethylenediamine (2:1)
- Vasofilina