CAS 317318-84-6

2-[4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid

Description:

The chemical substance known as 2-[4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid, with the CAS number 317318-84-6, is a complex organic compound characterized by its unique structural features. It contains a thiazole ring, which is a five-membered heterocyclic compound containing sulfur and nitrogen, contributing to its biological activity. The presence of a fluorinated aromatic group enhances its lipophilicity and may influence its pharmacokinetic properties. This compound is likely to exhibit specific interactions with biological targets, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. Its functional groups, including the carboxylic acid and ether moieties, suggest potential for hydrogen bonding and reactivity in various chemical environments. Overall, the compound's intricate structure and functional characteristics position it as a candidate for further investigation in therapeutic applications, although specific biological activity and safety profiles would require detailed experimental studies.

Formula: C₂₁H₁₇F₄NO₃S₂

InChI: InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)

InChI key: InChIKey=HWVNEWGKWRGSRK-UHFFFAOYSA-N

SMILES: C(SC1=CC(C)=C(OCC(O)=O)C=C1)C=2SC(=NC2C)C3=CC(F)=C(C(F)(F)F)C=C3

Synonyms:

• 2-[4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid
• Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-
• Acetic acid, [4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-
• GWδ 0742
• Gw 0742
• Gw 0742X
• Gw 610742
• Gw0742
• {4-[({2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid

[4-[[2-[3-Fluoro-4-(Trifluoromethyl)Phenyl]-4-Methyl-5-Thiazolyl]Methyl]Thio]-2-Methylphenoxy] Acetic Acid

CAS: 317318-84-6

[4-[[2-[3-Fluoro-4-(Trifluoromethyl)Phenyl]-4-Methyl-5-Thiazolyl]Methyl]Thio]-2-Methylphenoxy] Acetic Acid

Purity: 98%

Molecular weight: 471.49g/mol

Ref: 54-PC108535

GW0742

CAS: 317318-84-6

GW0742

Purity: ≥98%

Molecular weight: 471.49g/mol

Ref: 54-BUP10715

GW0742

CAS: 317318-84-6

Formula: C₂₁H₁₇F₄NO₃S₂

Molecular weight: 471.49

Ref: 7W-GL1624

GW0742

CAS: 317318-84-6

GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).

Formula: C₂₁H₁₇F₄NO₃S₂

Purity: 99.75% - 99.85%

Color and Shape: Solid

Molecular weight: 471.49

Ref: TM-T6524

GW0742

Controlled Product

CAS: 317318-84-6

Applications A small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
References Sznaidman, M.L., et al.: Bioorganic and Medicinal Chemistry Letters, 13, 1517 (2003)

Formula: C₂₁H₁₇F₄NO₃S₂

Color and Shape: Light Yellow

Molecular weight: 471.49

Ref: TR-G930000

GW 0742

CAS: 317318-84-6

Peroxisome proliferator-activated receptor PPARβ/Ύ agonist

Formula: C₂₁H₁₇F₄NO₃S₂

Purity: Min. 95%

Molecular weight: 471.49 g/mol

Ref: 3D-FG23723