CAS 317335-35-6

Presenilin-1 (331-349)-Cys (human, mouse)

Description:

Presenilin-1 (331-349)-Cys is a peptide derived from the presenilin-1 protein, which is implicated in the pathogenesis of Alzheimer's disease. This specific peptide sequence is known to play a role in the γ-secretase complex, which is crucial for the cleavage of amyloid precursor protein (APP) and the subsequent production of amyloid-beta peptides. The presence of cysteine in this sequence suggests potential for disulfide bond formation, which can influence the peptide's stability and interactions. The CAS number 317335-35-6 uniquely identifies this compound in chemical databases, facilitating its study and application in research. Characteristically, this peptide may exhibit properties such as solubility in aqueous solutions, potential for biological activity, and involvement in cellular signaling pathways. Its study is significant in understanding the molecular mechanisms underlying neurodegenerative diseases and may contribute to the development of therapeutic strategies targeting Alzheimer's disease.

Formula: C₉₂H₁₃₀N₂₈O₃₇S

Synonyms:

• H-Asn-Asp-Asp-Gly-Gly-Phe-Ser-Glu-Glu-Trp-Glu-Ala-Gln-Arg-Asp-Ser-His-Leu-Gly-Cys-Oh
• L-Cysteine,L-asparaginyl-L-a-aspartyl-L-a-aspartylglycylglycyl-L-phenylalanyl-L-seryl-L-a-glutamyl-L-a-glutamyl-L-tryptophyl-L-a-glutamyl-L-alanyl-L-glutaminyl-L-arginyl-L-a-aspartyl-L-seryl-L-histidyl-L-leucylglycyl-

Presenilin-1 (331-349)-Cys (human, mouse) trifluoroacetate salt

CAS: 317335-35-6

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Formula: C₉₂H₁₃₀N₂₈O₃₇S

Purity: Min. 95%

Molecular weight: 2,252.25 g/mol

Ref: 3D-FP109144