CAS 31752-99-5

[1,1′-Biphenyl]-4-carboxylic acid, (3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl ester

Description:

The chemical substance known as [1,1′-Biphenyl]-4-carboxylic acid, (3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl ester, with the CAS number 31752-99-5, is a complex organic compound characterized by its biphenyl and cyclopentafuran moieties. This compound features a carboxylic acid functional group, which contributes to its acidity and potential reactivity in various chemical reactions. The presence of the hexahydro structure indicates a saturated cyclic component, while the hydroxymethyl group suggests potential for hydrogen bonding and reactivity. The stereochemistry, denoted by the (3aR,4S,5R,6aS) configuration, implies specific spatial arrangements of atoms that can influence the compound's biological activity and interactions. Such compounds may exhibit interesting properties, including potential applications in pharmaceuticals or as intermediates in organic synthesis. Overall, the unique combination of functional groups and stereochemistry makes this compound a subject of interest in both synthetic and medicinal chemistry.

Formula: C₂₁H₂₀O₅

InChI: InChI=1S/C21H20O5/c22-12-17-16-10-20(23)25-18(16)11-19(17)26-21(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,16-19,22H,10-12H2/t16-,17-,18+,19-/m1/s1

InChI key: InChIKey=SZJVIFMPKWMGSX-AKHDSKFASA-N

SMILES: C(O)[C@@H]1[C@@]2([C@](C[C@H]1OC(=O)C3=CC=C(C=C3)C4=CC=CC=C4)(OC(=O)C2)[H])[H]

Synonyms:

• (-) Corey lactone 4-PHENYTLBENZOATE
• (-)-Corey Lactone 4-Phenyl Benzoate
• (-)-Corey lactone
• (-)Corey lactone phenylbenzoate
• (3aalpha,4alpha,5beta,6aalpha)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1'-biphenyl-4-carboxylate
• 2H-Cyclopenta[b]furan, [1,1′-biphenyl]-4-carboxylic acid deriv.
• 4-(hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl biphenyl-4-carboxylate
• 4-Biphenylcarboxylic acid, 5-ester with 3,3aα,4,5,6,6aα-hexahydro-5β-hydroxy-4α-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one, (-)-
• Coreylactone4-phenylbenzoate
• [1,1'-Biphenyl]-4-carboxylic acid, (3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl ester
• [1,1′-Biphenyl]-4-carboxylic acid, hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl ester, [3aR-(3aα,4α,5β,6aα)]-

(3aR,4S,5R,6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl Biphenyl-4-carboxylate

CAS: 31752-99-5

Formula: C₂₁H₂₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 352.3805

Ref: IN-DA003BQQ

(-)-Corey Lactone 4-Phenylbenzoate

CAS: 31752-99-5

Formula: C₂₁H₂₀O₅

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 352.39

Ref: 3B-C2756

(-)Corey lactone 4-phenylbenzoate

CAS: 31752-99-5

(-)Corey lactone 4-phenylbenzoate

Purity: 98%

Molecular weight: 352.38g/mol

Ref: 54-OR46130

(3aR,4S,5R,6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl Biphenyl-4-carboxylate

CAS: 31752-99-5

Purity: 98.0%

Color and Shape: Liquid, No data available.

Molecular weight: 352.385986328125

Ref: 10-F544827

(-)-Corey Lactone

Controlled Product

CAS: 31752-99-5

Applications Key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α.
References Carpio, H., et al.: Prostaglandins, 33, 169 (1987), Resul, B., et al.: J. Med. Chem., 36, 243 (1993),

Formula: C₂₁H₂₀O₅

Color and Shape: Neat

Molecular weight: 352.38

Ref: TR-C695000

(-)-Corey lactone 4-phenylbenzoate

CAS: 31752-99-5

Corey lactone 4-phenylbenzoate is an efficient, large-scale preparation of (-)-Corey lactone. It is synthesized in two steps from 4-phenylbenzoic acid and ethyl acetoacetate. Corey lactone 4-phenylbenzoate has been used for the synthesis of a variety of natural products. This compound is also a precursor to the synthesis of other compounds, such as 3-amino-4-(2'-hydroxyethoxy)benzaldehyde.

Formula: C₂₁H₂₀O₅

Purity: Min. 95%

Molecular weight: 352.38 g/mol

Ref: 3D-FC08664