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CAS 31828-50-9

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Cephradine dihydrate

Description:
Cephradine dihydrate is a semi-synthetic antibiotic belonging to the cephalosporin class, primarily used to treat bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective in treating respiratory tract infections, skin infections, and urinary tract infections. The chemical structure of cephradine includes a beta-lactam ring, which is essential for its antibacterial activity, as it inhibits bacterial cell wall synthesis. As a dihydrate, it contains two molecules of water, which can influence its solubility and stability. Cephradine is typically administered orally and is known for its relatively good absorption in the gastrointestinal tract. Its pharmacokinetics include a moderate half-life, necessitating multiple doses for sustained therapeutic effect. Common side effects may include gastrointestinal disturbances and allergic reactions, similar to other beta-lactam antibiotics. Overall, cephradine dihydrate is a valuable option in the antibiotic arsenal, particularly for patients with specific bacterial infections.
Formula:C16H19N3O4SH2O
InChI:InChI=1S/C16H19N3O4S.2H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;;/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23);2*1H2/t10-,11-,15-;;/m1../s1
InChI key:InChIKey=HBKDHIDYMXXJLI-OEDJVVDHSA-N
SMILES:O=C1N2[C@@]([C@@H]1NC([C@H](N)C=3CC=CCC3)=O)(SCC(C)=C2C(O)=O)[H].O
Synonyms:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[2-amino-2-(1,4-cyclohexadien-1-yl)acetamido]-3-methyl-8-oxo-, hydrate, <span class="text-smallcaps">D</span>-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-, hydrate (1:2), (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, dihydrate,(6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[2-amino-2-(1,4-cyclohexadien-1-yl)acetamido]-3-methyl-8-oxo-, hydrate,D-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-,hydrate (1:2), (6R,7R)-
  • Cefradine dihydrate
  • Cephradine dihydrate
  • Cephradine hydrate
  • Sefril hydrate
  • Velosef hydrate
  • See more synonyms
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