CAS 31828-68-9
:L-Homocysteine thiolactone hydrochloride
Description:
L-Homocysteine thiolactone hydrochloride is a derivative of the amino acid homocysteine, characterized by the presence of a thiolactone functional group. This compound is typically encountered as a white to off-white crystalline powder and is soluble in water, which facilitates its use in biochemical applications. It plays a significant role in the study of homocysteine metabolism and is often utilized in research related to cardiovascular diseases and neurodegenerative disorders, as elevated levels of homocysteine are associated with various health issues. The hydrochloride form indicates the presence of hydrochloric acid, which enhances its solubility and stability. L-Homocysteine thiolactone can participate in various chemical reactions, including acylation and thiol-disulfide exchange, making it a valuable reagent in organic synthesis and medicinal chemistry. Its reactivity is largely attributed to the thiolactone ring, which can undergo hydrolysis to release homocysteine, thus contributing to its biological significance. Proper handling and storage conditions are essential to maintain its integrity and efficacy in laboratory settings.
Formula:C4H7NOS·ClH
InChI:InChI=1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key:InChIKey=ZSEGSUBKDDEALH-DFWYDOINSA-N
SMILES:N[C@@H]1C(=O)SCC1.Cl
Synonyms:- (3S)-3-aminodihydrothiophen-2(3H)-one hydrochloride
- (S)-3-Aminodihydrothiophen-2(3H)-one HCl
- (S)-3-Aminodihydrothiophen-2(3H)-one hydrochloride
- 2(3H)-Thiophenone, 3-aminodihydro-, hydrochloride (1:1), (3S)-
- 2(3H)-Thiophenone, 3-aminodihydro-, hydrochloride, (3S)-
- 2(3H)-Thiophenone, 3-aminodihydro-, hydrochloride, (S)-
- 2(3H)-Thiophenone, 3-aminodihydro-, hydrochloride, <span class="text-smallcaps">L</span>-
- <span class="text-smallcaps">L</span>-Homocysteine thiolactone hydrochloride
- L-Homocysteine thiolactone hydrochloride
- 2(3H)-Thiophenone, 3-aminodihydro-, hydrochloride, L-
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Found 10 products.
L-Homocysteine thiolactone hydrochloride
CAS:Formula:C4H8ClNOSPurity:98%Color and Shape:SolidMolecular weight:153.6304L-Homocysteine thiolactone hydrochloride
CAS:<p>L-Homocysteine thiolactone hydrochloride</p>Purity:≥98%Molecular weight:153.63g/mol(S)-3-Aminodihydrothiophen-2(3H)-One Hydrochloride
CAS:<p>(S)-3-Aminodihydrothiophen-2(3H)-One Hydrochloride</p>Purity:98%Molecular weight:153.63g/molL-Homocysteine thiolactone hydrochloride
CAS:Formula:C4H7NOS·HClPurity:≥ 96.0%Color and Shape:White powderMolecular weight:153.63L-Homocysteine Thiolactone HCl
CAS:Formula:C4H7NOS·HClColor and Shape:White To Off-White SolidMolecular weight:117.17 36.46L-Homocysteine thiolactone hydrochloride
CAS:<p>L-Homocysteine thiolactone hydrochloride is neurotoxic and can induce epilepsy and Alzheimer's disease.</p>Formula:C4H8ClNOSPurity:99.32%Color and Shape:SolidMolecular weight:153.63L-Homocysteine Thiolactone Hydrochloride
CAS:Controlled Product<p>Applications L-Homocysteine Thiolactone Hydrochloride is used to prepare substituted homocysteine analogs as inhibitors of peptidylglycine α-amidating monooxygenase. It is also used to synthesize (mercaptoacyl)alanylprolines as metalloprotease inhibitors.<br>References Erion, M., et al.: J. Med. Chem., 37, 4430 (1994); Slusarchyk, W., et al.: Bioorg. Med. Chem. Lett., 5, 753 (1995)<br></p>Formula:C4H8ClNOSColor and Shape:NeatMolecular weight:153.63L-Homocysteine thiolactone hydrochloride
CAS:<p>L-Homocysteine thiolactone hydrochloride is a synthetic radiotracer. It has been used as a positron emission tomography (PET) radiopharmaceutical to image brain tumors and other cancers. L-homocysteine thiolactone hydrochloride is synthesized from L-cysteine and aluminium chloride. The yield of this reaction is usually low, but can be increased by addition of sodium hydroxide or tetrabutylammonium bromide. L-homocysteine thiolactone hydrochloride has been shown to be an effective radiotracer for the detection of cancerous tissue in the brain, breast, and prostate.</p>Formula:C4H7NOS•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:153.63 g/mol(S)-3-Aminodihydrothiophen-2(3H)-one hydrochloride
CAS:Formula:C4H8ClNOSPurity:98%Molecular weight:153.62
