CAS 31828-71-4

Mexiletine

Description:

Mexiletine is a synthetic antiarrhythmic medication primarily used to treat ventricular arrhythmias. It belongs to the class of drugs known as class 1B antiarrhythmics, which work by stabilizing the cardiac cell membrane and reducing excitability. The chemical formula of mexiletine is C11H15N, and it features a piperidine ring structure, which contributes to its pharmacological properties. Mexiletine is typically administered orally and is known for its relatively rapid absorption and bioavailability. It is metabolized in the liver, primarily through cytochrome P450 enzymes, and has a moderate half-life, necessitating multiple doses throughout the day for sustained therapeutic effect. Common side effects may include gastrointestinal disturbances, dizziness, and tremors. Due to its mechanism of action, mexiletine is particularly effective in managing conditions associated with abnormal heart rhythms, making it a valuable option in the treatment of certain cardiac disorders. As with any medication, it is essential to use mexiletine under medical supervision to monitor for potential interactions and side effects.

Formula: C₁₁H₁₇NO

InChI: InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3

InChI key: InChIKey=VLPIATFUUWWMKC-UHFFFAOYSA-N

SMILES: O(CC(C)N)C1=C(C)C=CC=C1C

Synonyms:

• (.+-.)-2-Amino-1-(2',6'-dimethylphenoxy)propane
• (RS)-Mexiletine
• 1-(2',6'-Dimethylphenoxy)-2-aminopropane
• 1-(2,6-Dimethylphenoxy)-2-Propanamine
• 1-(2,6-Dimethylphenoxy)propan-2-amine
• 1-(2,6-Xylyloxy)-2-propylamine
• 1-(2′,6′-Dimethylphenoxy)-2-aminopropane
• 1-Methyl-2-(2,6-xylyloxy)ethylamine
• 2-(2-Aminopropoxy)-1,3-dimethylbenzene
• 2-Amino-1-(2,6-dimethylphenoxy)propane
• 2-Propanamine, 1-(2,6-dimethylphenoxy)-
• Ethylamine, 1-methyl-2-(2,6-xylyloxy)-
• Mexiletin
• Mexiletina
• [2-[(2,6-Dimethylphenyl)oxy]-1-methylethyl]amine
• dl-Mexiletine

2-Propanamine, 1-(2,6-dimethylphenoxy)-

CAS: 31828-71-4

Formula: C₁₁H₁₇NO

Purity: %

Color and Shape: Solid

Molecular weight: 179.2588

Ref: IN-DA00BXSR

Mexiletine

CAS: 31828-71-4

Mexiletine

Purity: ≥95%

Molecular weight: 179.26g/mol

Ref: 54-OR1007727

Mexiletine

CAS: 31828-71-4

Mexiletine is a non-selective voltage-gated sodium channel blocker.

Formula: C₁₁H₁₇NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 179.26

Ref: TM-T21427

1-(2,6-Dimethylphenoxy)-2-aminopropane

Controlled Product

CAS: 31828-71-4

Formula: C₁₁H₁₇NO

Color and Shape: Neat

Molecular weight: 179.25

Ref: TR-D481040

Mexiletine

CAS: 31828-71-4

Mexiletine is a drug that belongs to the class of drugs called antiarrhythmics. It is used for the treatment of ventricular arrhythmias and for removing cardiac conduction abnormalities. Mexiletine acts by inhibiting the release of calcium ions from the sarcoplasmic reticulum, which leads to a reduction in excitability of the heart muscle. Mexiletine has been shown to have a matrix effect on bacterial DNA, which may be due to its ability to bind with dinucleotide phosphate or its inhibitory effects on hypersensitivity syndrome. Mexiletine also has an effect on cardiac tissue, leading to decreased contractility and increased relaxation time. The mechanism by which mexiletine leads to these effects is not well understood but may be related to its ability to interact with ion channels in myocardial cells or alter protein function in these cells. Mexiletine has been shown to have some drug interactions, such as with other drugs that are metabolized through cy

Formula: C₁₁H₁₇NO

Purity: Min. 95%

Color and Shape: Yellow Clear Liquid

Molecular weight: 179.26 g/mol

Ref: 3D-FM153231