CAS 31868-18-5

Mexazolam

Description:

Mexazolam is a benzodiazepine derivative primarily used for its anxiolytic and sedative properties. It is characterized by its ability to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased neuronal inhibition and a calming effect on the central nervous system. Mexazolam is typically administered in tablet form and is indicated for the treatment of anxiety disorders and panic attacks. Its pharmacological profile includes anxiolytic, muscle relaxant, and anticonvulsant effects, making it versatile in clinical applications. The substance has a relatively rapid onset of action, and its effects can last for several hours, depending on the dosage and individual metabolism. However, like other benzodiazepines, mexazolam carries a risk of dependence, tolerance, and withdrawal symptoms with prolonged use. It is important for users to follow medical guidance to mitigate these risks. Additionally, mexazolam may interact with other medications and substances, necessitating careful consideration in polypharmacy situations.

Formula: C₁₈H₁₆Cl₂N₂O₂

InChI: InChI=1S/C18H16Cl2N2O2/c1-11-10-24-18(13-4-2-3-5-15(13)20)14-8-12(19)6-7-16(14)21-17(23)9-22(11)18/h2-8,11H,9-10H2,1H3,(H,21,23)

InChI key: InChIKey=ANUCDXCTICZJRH-UHFFFAOYSA-N

SMILES: CC1N2C(C=3C(NC(=O)C2)=CC=C(Cl)C3)(OC1)C4=C(Cl)C=CC=C4

Synonyms:

• 10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
• 10-Chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
• 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,7,11b-tetrahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
• Brn 1091849
• Cs 386
• Melex
• Mexazolam [INN:JAN]
• Mexazolamum
• Mexazolamum [INN-Latin]
• Oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl-
• Unii-S5969B6237
• Mexazolam

Mexazolam

Controlled Product

CAS: 31868-18-5

Applications Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway.
References Ferreira, L., et al.: Clin. Drug. Investig., 23, 235 (2003); Ishigami, M., et al.: Drug. Metab. Dispos., 30, 904 (2002); Sheridan, R.P., et al.: J. Med. Chem., 50, 3173 (2007);

Formula: C₁₈H₁₆Cl₂N₂O₂

Color and Shape: Neat

Molecular weight: 363.24

Ref: TR-M340600

Mexazolam (1 mg/mL in Acetonitrile)

Controlled Product

CAS: 31868-18-5

Formula: C₁₈H₁₆Cl₂N₂O₂

Color and Shape: Colourless

Molecular weight: 363.24

Ref: TR-KIT6145

Mexazolam

Controlled Product

CAS: 31868-18-5

Mexazolam is an analog of indirubin, a natural compound that has been shown to have anticancer properties. Mexazolam inhibits kinase activity in human cancer cells, leading to apoptosis and the inhibition of tumor growth. This drug has been shown to be effective against a variety of cancers, including breast, lung, and prostate cancer. Mexazolam works by inhibiting the activity of protein kinases, which are enzymes that play a key role in cell division and proliferation. It is also used as an inhibitor for Chinese hamster ovary (CHO) cell proliferation in urine samples. Its potency as an anticancer agent makes it a promising candidate for further development as a cancer therapy.

Formula: C₁₈H₁₆Cl₂N₂O₂

Purity: Min. 95%

Molecular weight: 363.2 g/mol

Ref: 3D-GBA86818

Mexazolam

CAS: 31868-18-5

Mesazolam is a benzodiazepine drug.

Formula: C₁₈H₁₆Cl₂N₂O₂

Color and Shape: Solid

Molecular weight: 363.24

Ref: TM-T33371