CAS 319425-66-6

Cf 1743

Description:

The chemical substance referred to as "Cf 1743" with the CAS number "319425-66-6" is a synthetic compound that belongs to the class of organofluorine compounds. It is characterized by the presence of fluorine atoms, which significantly influence its chemical properties, including stability and reactivity. Organofluorine compounds are known for their unique characteristics, such as high thermal stability, resistance to degradation, and hydrophobicity, making them useful in various applications, including pharmaceuticals, agrochemicals, and materials science. The specific structure and functional groups of Cf 1743 would determine its reactivity and potential applications. Additionally, the compound's safety profile, including toxicity and environmental impact, would need to be assessed for practical use. As with many synthetic chemicals, proper handling and disposal procedures are essential to mitigate any risks associated with its use. Further research and characterization would provide more detailed insights into its properties and potential applications in various fields.

Formula: C₂₂H₂₆N₂O₅

InChI: InChI=1S/C22H26N2O5/c1-2-3-4-5-14-6-8-15(9-7-14)18-10-16-12-24(22(27)23-21(16)29-18)20-11-17(26)19(13-25)28-20/h6-10,12,17,19-20,25-26H,2-5,11,13H2,1H3/t17-,19+,20+/m0/s1

InChI key: InChIKey=MFGSDSRTGUVZQG-DFQSSKMNSA-N

SMILES: O=C1N=C2C(=CN1[C@@H]3O[C@H](CO)[C@@H](O)C3)C=C(O2)C4=CC=C(CCCCC)C=C4

Synonyms:

• Furo[2,3-d]pyrimidin-2(3H)-one, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)-
• 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-6-(4-pentylphenyl)furo[2,3-d]pyrimidin-2(3H)-one
• Cf 1743

CF-1743

CAS: 319425-66-6

CF-1743

Purity: ≥98%

Molecular weight: 398.45g/mol

Ref: 54-BUP12356

CF 1743-d7 (Major)

Controlled Product

CAS: 319425-66-6

Applications CF 1743-d7 is labelled Cf 1743 (C291710) which is an orally available nucleoside analogue drug with antiviral activity. It is a potent and selective inhibitor of varicella zoster virus.
References McGuigan, C., et al.: J. Med. Chem., 43, 4993 (2000); McGuigan, C., et al.: J. Antimicro. Chemother., 60, 1316 (2007); Andrei, G., et al.: Antimicro. Agents Chemother., 49, 1081 (2005)

Formula: C₂₂D₇H₁₉N₂O₅

Color and Shape: Neat

Molecular weight: 405.495

Ref: TR-C291712

CF 1743

Controlled Product

CAS: 319425-66-6

Applications CF 1743 is an orally available nucleoside analogue drug with antiviral activity. It is a potent and selective inhibitor of varicella zoster virus.
References McGuigan, C., et al.: J. Med. Chem., 43, 4993 (2000); McGuigan, C., et al.: J. Antimicro. Chemother., 60, 1316 (2007); Andrei, G., et al.: Antimicro. Agents Chemother., 49, 1081 (2005)

Formula: C₂₂H₂₆N₂O₅

Color and Shape: Neat

Molecular weight: 398.45

Ref: TR-C291710

CF 1743-d7 (Major)

CAS: 319425-66-6

CF 1743-d7 is a synthetic antiviral drug that was developed to treat herpes simplex virus, shingles, and hepatitis. It has potent antiviral potency against a variety of viruses, including papilloma virus and influenza virus. CF 1743-d7 has been shown to inhibit the synthesis of viral DNA in cell culture and to be metabolized by cytochrome P450 enzymes in liver cells. This drug has lipophilic properties, which allows it to cross the blood-brain barrier. CF 1743-d7 has pharmacokinetic properties that are similar to other drugs in its class; however, it does not show significant accumulation in lymphocytes or macrophages.

Formula: C₂₂H₁₉D₇N₂O₅

Purity: Min. 95%

Molecular weight: 405.5 g/mol

Ref: 3D-UMA42566

CF-1743

CAS: 319425-66-6

CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.

Formula: C₂₂H₂₆N₂O₅

Purity: 99.6% - 99.79%

Color and Shape: Solid

Molecular weight: 398.45

Ref: TM-T26987