CAS 319494-39-8

AC-VEID-CHO

Description:

AC-VEID-CHO, with the CAS number 319494-39-8, is a chemical compound that belongs to the class of peptide aldehydes. It is characterized by its specific structure, which includes a peptide sequence that is often utilized in biochemical research, particularly in studies related to apoptosis and cell signaling. The compound is known for its ability to selectively inhibit certain caspases, which are crucial enzymes in the apoptotic pathway. This selectivity makes AC-VEID-CHO a valuable tool in understanding the mechanisms of programmed cell death and in the development of therapeutic strategies for diseases where apoptosis is dysregulated. Additionally, the aldehyde functional group in its structure contributes to its reactivity and potential applications in various chemical reactions. As with many peptide-based compounds, its stability and solubility can vary based on environmental conditions, making proper handling and storage essential for maintaining its integrity in experimental settings.

Formula: C₂₂H₃₆N₄O₉

Synonyms:

• AC-VAL-GLU-ILE-ASP-ALDEHYDE
• CASPASE 6 (MCH 2) INHIBITOR 1
• AC-VAL-GLU-ILE-ASP-CHO
• N-Acetyl-Val-Glu-Ile-Asp-al
• AC-VAL-GLU-ILE-ASP-ALDEHYDE (PSEUDO ACID)
• CASPASE-6 INHIBITOR II
• AC-VEID-ALDEHYDE
• CASPASE-6 INHIBITOR (ALDEHYDE)
• CASPASE-6 INHIBITOR II, CELL-PERMEABLE
• N-ACETYL-VAL-GLU-ILE-ASP-CHO (ALDEHYDE)
• VEID-CHO, CELL-PERMEABLE
• Ac-VEID-CHO trifluoroacetate salt
• N-ACETYL-VAL-GLU-ILE-ASPARTINAL
• AC-VEID-CHO
• L-Isoleucinamide, N-acetyl-L-valyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-
• ACETYL-L-VALYL-L-GLUTAMYL-L-ISOLEUCYL-L-ASPART-1-AL

Ac-Val-Glu-Ile-Asp-aldehyde (pseudo acid)

CAS: 319494-39-8

AC-VEID-CHO, a specific inhibitor of caspase-6 (Mch2).

Formula: C₂₂H₃₆N₄O₉

Purity: 96.7%

Molecular weight: 500.55

Ref: 01-4027894

Ac-Val-Glu-Ile-Asp-H (aldehyde)

CAS: 319494-39-8

Ac-Val-Glu-Ile-Asp-H (aldehyde) is a synthetic peptide that is used as an inhibitor to study the effects of protein interactions. Ac-Val-Glu-Ile-Asp-H (aldehyde) binds to the active site of the enzyme, which prevents the enzyme from functioning and can be used as a research tool. Ac-Val-Glu-Ile-Asp-H (aldehyde) has been shown to activate some receptors and ligands, such as ion channels and antibodies.

Formula: C₂₂H₃₆N₄O₉

Purity: Min. 95%

Molecular weight: 500.54 g/mol

Ref: 3D-IVA-3182-V

Ac-Val-Glu-Ile-Asp-aldehyde (pseudo acid)

CAS: 319494-39-8

Ac-Val-Glu-Ile-Asp-aldehyde is a pseudo acid that has been shown to induce apoptotic cell death in cultured cells. It is localized in the cerebellar granule and mitochondria of HL-60 cells and HK-2 cells. Ac-Val-Glu-Ile-Asp-aldehyde induces necrotic cell death when it binds to the serine protease zymogen, which is localized in the mitochondrial membrane. It also induces apoptosis by disrupting the mitochondrial membrane potential, leading to a release of cytochrome c into the cytosol. Ac-Val-Glu-Ile-Asp-aldehyde can bind to annexin and tubule cells, which are important for β cell function.

Formula: C₂₂H₃₆N₄O₉

Purity: Min. 95%

Molecular weight: 500.54 g/mol

Ref: 3D-FA111077