CAS 32140-51-5

Coenzyme A, S-acetate, lithium salt (1:?)

Description:

Coenzyme A, S-acetate, lithium salt (1:?) is a derivative of coenzyme A, which plays a crucial role in various biochemical processes, particularly in the metabolism of fatty acids and the synthesis of acetyl-CoA. This compound is characterized by its ability to participate in acyl group transfer reactions, facilitating the conversion of fatty acids into their active forms for energy production. The lithium salt form suggests enhanced solubility and stability in aqueous solutions, making it suitable for various biochemical applications. Coenzyme A itself is essential for the activation of acyl groups, and its acetate derivative is particularly important in metabolic pathways, including the citric acid cycle. The presence of lithium may also influence the compound's interaction with biological systems, potentially affecting its bioavailability and efficacy. Overall, this compound is significant in metabolic research and may have implications in studies related to energy metabolism and enzymatic reactions.

Formula: C₂₃H₃₈N₇O₁₇P₃S·xLi

InChI: InChI=1S/C23H38N7O17P3S.Li/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30;/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38);/t13-,16-,17-,18+,22-;/m1./s1

InChI key: InChIKey=MQDBECZUJONFAI-QJBWUGSNSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(C)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O.[Li]

Synonyms:

• Coenzyme A, S-acetate, lithium salt
• Coenzyme A, S-acetate, lithium salt (1:?)
• Lithium acetyl-CoA

ACETYL COENZYME A (C2

CAS: 32140-51-5

Formula: C₂₃H₃₈LiN₇O₁₇P₃S

Purity: 83%

Molecular weight: 816.5118

Ref: IN-DA00CILN

Acetyl Coenzyme A, Lithium salt

CAS: 32140-51-5

Acetyl Coenzyme A, Lithium salt

Purity: ≥ 95%

Molecular weight: 809.57g/mol

Ref: 54-BI12187

Acetyl coenzyme A lithium salt

CAS: 32140-51-5

Formula: C₂₃H₃₈N₇O₁₇P₃S·xLi

Purity: ≥ 95%

Color and Shape: White to off-white or pale yellow powder

Molecular weight: 809.57 (free acid)

Ref: 7W-GL8669

Acetyl coenzyme A lithium

CAS: 32140-51-5

Acetyl-CoA lithium: central metabolic molecule, crucial for TCA cycle, oxidative phosphorylation, protein acetylation, and lipid synthesis.

Formula: C₂₃H₃₈N₇O₁₇P₃S

Color and Shape: Solid

Molecular weight: 809.57

Ref: TM-T73796

Acetyl coenzyme A lithium

CAS: 32140-51-5

Acetyl coenzyme A lithium salt is a drug that inhibits the production of acetyl-CoA, which is an important molecule in the metabolism of fatty acids. This drug has been shown to be effective against cancerous cells by inhibiting the synthesis of lysine residues and carnitine. Acetyl coenzyme A lithium salt has also been shown to inhibit the growth of typhimurium, which may be due to its ability to inhibit NADPH-cytochrome p450 reductase. Acetyl coenzyme A lithium salt has not been shown to have any carcinogenic potential in humans, but it has been shown to have carcinogenic potential in animal models.

Formula: C₂₃H₃₈N₇O₁₇P₃S•Lix

Purity: Min. 85%

Color and Shape: Powder

Molecular weight: 809.57 g/mol

Ref: 3D-NA45964

Acetyl Coenzyme A, Lithium salt

CAS: 32140-51-5

Purity: 95%

Molecular weight: 813.119

Ref: 10-C300010

Acetyl Coenzyme A Lithium Salt

CAS: 32140-51-5

Applications Acetyl Coenzyme A Lithium Salt is an important molecule in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to acyl carrier proteins and formyltetrahydrofolate dehydrogenase.
References Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968); Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010);

Formula: C₂₃H₃₈N₇O₁₇P₃S·Lix

Color and Shape: Neat

Molecular weight: 809.57 + (6.94)x

Ref: TR-A172145