CAS 3219-63-4

1-(Trimethylsilyl)methanol

Description:

1-(Trimethylsilyl)methanol, with the CAS number 3219-63-4, is an organosilicon compound characterized by the presence of a trimethylsilyl group attached to a methanol moiety. This compound typically appears as a colorless liquid and is known for its stability and low volatility. It features a silicon atom bonded to three methyl groups and a hydroxymethyl group, which contributes to its unique reactivity and solubility properties. The trimethylsilyl group enhances the compound's hydrophobic characteristics, making it useful in various applications, including as a protecting group in organic synthesis and in the preparation of silyl ethers. Additionally, 1-(Trimethylsilyl)methanol can participate in reactions typical of alcohols, such as nucleophilic substitutions and dehydration, while also exhibiting the ability to stabilize reactive intermediates. Its utility in analytical chemistry, particularly in mass spectrometry and chromatography, is notable due to its ability to improve the volatility and detectability of certain analytes. Overall, this compound serves as a valuable tool in both synthetic and analytical chemistry.

Formula: C₄H₁₂OSi

InChI: InChI=1/C3H9OS.ClH/c1-5(2,3)4;/h1-3H3;1H/q+1;/p-1

InChI key: InChIKey=ZQKNBDOVPOZPLY-UHFFFAOYSA-N

SMILES: [Si](CO)(C)(C)C

Synonyms:

• (Hydroxymethyl)trimethylsilane
• (Trimethylsilyl)Methanol
• 1-(Trimethylsilyl)methanol
• 1-Trimethylsilylmethanol
• Methanol, (trimethylsilyl)-
• Methanol, 1-(trimethylsilyl)-
• NSC 96777
• Hydroxymethyltrimethylsilane
• (hydroxymethyl)trimethyl-silan
• TRIMETHYLHYDROXYMETHYLSILANE
• (trimethylsilyl)-methano
• 1-TRIMETHYLSILYLMETHANOL, 98+%

1-Trimethylsilylmethanol, 95%

CAS: 3219-63-4

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent. This Thermo Scientific Chemicals brand product was ori

Formula: C₄H₁₂OSi

Purity: 95%

Color and Shape: Liquid, Clear colorless

Molecular weight: 104.22

Ref: 02-L04251

1-Trimethylsilylmethanol

CAS: 3219-63-4

1-Trimethylsilylmethanol

Purity: 98%

Molecular weight: 104.22g/mol

Ref: 54-OR322469

Trimethylsilylmethanol

CAS: 3219-63-4

Formula: C₄H₁₂OSi

Purity: >97.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 104.22

Ref: 3B-T1250

(Trimethylsilyl)methanol

CAS: 3219-63-4

S19675 - (Trimethylsilyl)methanol

Formula: C₄H₁₂OSi

Purity: 98%

Color and Shape: Liquid

Molecular weight: 104.224

Ref: 10-S19675