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CAS 322-35-0

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Benserazide

Description:
Benserazide is a chemical compound primarily known for its role as a peripheral decarboxylase inhibitor, particularly in the treatment of Parkinson's disease. It is often used in conjunction with levodopa to enhance the latter's efficacy by preventing its conversion to dopamine outside the central nervous system, thereby increasing its availability in the brain. Benserazide is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms. The compound is typically presented as a white to off-white crystalline powder, and it is soluble in water and various organic solvents. Its mechanism of action involves the inhibition of the enzyme aromatic L-amino acid decarboxylase, which is crucial for the metabolism of levodopa. Benserazide is generally well-tolerated, but like any medication, it may have side effects, including gastrointestinal disturbances and potential interactions with other drugs. Its pharmacokinetics and safety profile make it a valuable adjunct in the management of Parkinson's disease symptoms.
Formula:C10H15N3O5
InChI:InChI=1/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)
InChI key:InChIKey=BNQDCRGUHNALGH-UHFFFAOYSA-N
SMILES:C(NNC(C(CO)N)=O)C1=C(O)C(O)=C(O)C=C1
Synonyms:
  • 2-Amino-3-Hydroxy-2'-(2,3,4-Trihydroxybenzyl)Propionohydrazide
  • 2-Amino-3-hydroxy-N′-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
  • 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide (non-preferred name)
  • <span class="text-smallcaps">DL</span>-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
  • <span class="text-smallcaps">DL</span>-Seryltrihydroxybenzylhydrazine
  • Benoxacor Chem-1468
  • N-(<span class="text-smallcaps">DL</span>-Seryl)-N′-(2,3,4-trihydroxybenzyl)hydrazine
  • N<sup>1</sup>-(<span class="text-smallcaps">DL</span>-Seryl)-N<sup>2</sup>-(2,3,4-trihydroxybenzyl)hydrazine
  • Serazide
  • Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide
  • See more synonyms
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