CAS 322-35-0

Benserazide

Description:

Benserazide is a chemical compound primarily known for its role as a peripheral decarboxylase inhibitor, particularly in the treatment of Parkinson's disease. It is often used in conjunction with levodopa to enhance the latter's efficacy by preventing its conversion to dopamine outside the central nervous system, thereby increasing its availability in the brain. Benserazide is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms. The compound is typically presented as a white to off-white crystalline powder, and it is soluble in water and various organic solvents. Its mechanism of action involves the inhibition of the enzyme aromatic L-amino acid decarboxylase, which is crucial for the metabolism of levodopa. Benserazide is generally well-tolerated, but like any medication, it may have side effects, including gastrointestinal disturbances and potential interactions with other drugs. Its pharmacokinetics and safety profile make it a valuable adjunct in the management of Parkinson's disease symptoms.

Formula: C₁₀H₁₅N₃O₅

InChI: InChI=1/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)

InChI key: InChIKey=BNQDCRGUHNALGH-UHFFFAOYSA-N

SMILES: C(NNC(C(CO)N)=O)C1=C(O)C(O)=C(O)C=C1

Synonyms:

• 2-Amino-3-Hydroxy-2'-(2,3,4-Trihydroxybenzyl)Propionohydrazide
• 2-Amino-3-hydroxy-N′-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
• 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide (non-preferred name)
• <span class="text-smallcaps">DL</span>-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
• <span class="text-smallcaps">DL</span>-Seryltrihydroxybenzylhydrazine
• Benoxacor Chem-1468
• N-(<span class="text-smallcaps">DL</span>-Seryl)-N′-(2,3,4-trihydroxybenzyl)hydrazine
• N¹-(<span class="text-smallcaps">DL</span>-Seryl)-N²-(2,3,4-trihydroxybenzyl)hydrazine
• Serazide
• Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide
• Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, <span class="text-smallcaps">DL</span>-
• Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
• DL-Seryltrihydroxybenzylhydrazine
• Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, DL-
• DL-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
• N-(DL-Seryl)-N'-(2,3,4-trihydroxybenzyl)hydrazine
• Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, DL-(8CI)
• BENSERAZIDE
• Benserazide Hydrochloride 14919-77-8/Base:
• Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide (7CI)
• BENSERASZIDE
• 2-(2,3,4-trihydroxybenzyl)hyrazide,dl-serin
• BenserazideBase
• N1-(DL-Seryl)-N2-(2,3,4-trihydroxybenzyl)hydrazine

Benserazide Hydrochloride

CAS: 14919-77-8, 322-35-0

Formula: C₁₀H₁₅N₃O₅·HCl

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 293.70

Ref: 3B-B4108

Benserazide-d3

CAS: 322-35-0

Formula: C₁₀H₁₂N₃O₅D₃

Molecular weight: 260.27

Ref: 4Z-B-081

Biapenem Dimer A

CAS: 322-35-0

Formula: C₃₀H₃₆N₈O₈S₂

Molecular weight: 700.80

Ref: 4Z-B-081001

Benserazide

CAS: 322-35-0

Formula: C₁₀H₁₅N₃O₅

Molecular weight: 257.25

Ref: ST-EA-CP-B45007

Benserazide

CAS: 322-35-0

Benserazide blocks dopa decarboxylase; paired with levodopa for Parkinson's to boost CNS dopamine levels and lower dosage.

Formula: C₁₀H₁₅N₃O₅

Color and Shape: Solid

Molecular weight: 257.24

Ref: TM-T1517L