CAS 32233-40-2

(3aR,4S,5R,6aS)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one

Description:

The chemical substance known as (3aR,4S,5R,6aS)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one, with the CAS number 32233-40-2, is a bicyclic compound characterized by its unique fused ring structure. This compound features multiple stereocenters, which contribute to its specific three-dimensional configuration and potentially influence its biological activity. The presence of hydroxyl groups (-OH) indicates that it may exhibit polar characteristics, enhancing its solubility in water and its reactivity in various chemical reactions. The furanone moiety suggests that it may participate in reactions typical of lactones and cyclic ethers, making it of interest in organic synthesis and medicinal chemistry. Additionally, the stereochemistry of the compound may play a crucial role in its interaction with biological targets, which could be relevant for pharmacological applications. Overall, this compound's structural features suggest potential utility in various fields, including drug development and materials science, although specific applications would depend on further research and characterization.

Formula: C₈H₁₂O₄

InChI: InChI=1/C8H12O4/c9-3-5-4-1-8(11)12-7(4)2-6(5)10/h4-7,9-10H,1-3H2/t4-,5-,6-,7+/m1/s1

InChI key: InChIKey=VYTZWRCSPHQSFX-GBNDHIKLSA-N

SMILES: C(O)[C@@H]1[C@@]2([C@](C[C@H]1O)(OC(=O)C2)[H])[H]

Synonyms:

• (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
• (-)-Corey's lactone diol
• (-)-Coreydiol
• (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
• (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, [3aR-(3aα,4α,5β,6aα)]-
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, stereoisomer
• 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-,(3aR,4S,5R,6aS)-
• Lactone diol
• (-)-Corey Lactone Diol
• (1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone
• (-)-COREY DIOL (COREY LACTONE)
• (1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,
• (3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLOPENT A[B]FURAN-2-ONE
• Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one.
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-HOCH2-2H-CYCLOPENTA(B)FURAN-2-ONE, 98%
• (-)-COREY LACTONE

(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%

CAS: 32233-40-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₂O₄

Purity: 98%

Molecular weight: 172.18

Ref: 02-H56119

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Formula: C₈H₁₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.1785

Ref: IN-DA0032AQ

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

CAS: 32233-40-2

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

Purity: 99%

Color and Shape: Solid

Molecular weight: 172.18g/mol

Ref: 54-OR52144

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol

Purity: ≥95%

Molecular weight: 172.18g/mol

Ref: 54-BUP18578

(-)-Corey Lactone Diol

CAS: 32233-40-2

Formula: C₈H₁₂O₄

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 172.18

Ref: 3B-H1418

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a pharmaceutical intermediate

Formula: C₈H₁₂O₄

Purity: 98%

Color and Shape: White To Beige-Brown Cryst Powder Or Crystals

Molecular weight: 172.18

Ref: TM-T8085

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Formula: C₈H₁₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.18

Ref: 10-F239043

(-)-Corey Lactone Diol

Controlled Product

CAS: 32233-40-2

Applications (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References Gal, Z. et al.: J. Chemother., 12, 274 (2000); Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008);

Formula: C₈H₁₂O₄

Color and Shape: Neat

Molecular weight: 172.18

Ref: TR-C694995

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a synthetic compound that is soluble in organic solvents. It is used for the synthesis of carbocyclic nucleosides, which are analogs of pyrimidine nucleosides. (-)-Corey lactone diol has been shown to inhibit cholesterol synthesis and the synthesis of alkene. (-)-Corey lactone diol also shows anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Formula: C₈H₁₂O₄

Purity: Min. 95%

Molecular weight: 172.18 g/mol

Ref: 3D-FC29747