CAS 32324-19-9

o-Toluenesulfonyl isocyanate

Description:

o-Toluenesulfonyl isocyanate, with the CAS number 32324-19-9, is an organic compound characterized by its isocyanate functional group attached to an o-toluenesulfonyl moiety. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly in forming ureas and carbamates through reactions with amines and alcohols. It is soluble in organic solvents such as acetone and dichloromethane but has limited solubility in water. The presence of the sulfonyl group enhances its electrophilic character, making it a useful reagent in organic synthesis, especially in the preparation of sulfonamide derivatives. However, o-toluenesulfonyl isocyanate is also considered hazardous; it can be irritating to the skin, eyes, and respiratory system, and appropriate safety measures should be taken when handling it. Its applications extend to the pharmaceutical and agrochemical industries, where it serves as an intermediate in the synthesis of various biologically active compounds.

Formula: C₈H₇NO₃S

InChI: InChI=1/C8H7NO3S/c1-7-4-2-3-5-8(7)13(11,12)9-6-10/h2-5H,1H3

SMILES: Cc1ccccc1S(=O)(=O)N=C=O

Synonyms:

• 2-Methylbenzenesulfonyl isocyanate
• Benzenesulfonyl Isocyanate, 2-Methyl-
• 2-Toluenesulfonyl Isocyanate

2-Toluenesulfonyl isocyanate

CAS: 32324-19-9

Formula: C₈H₇NO₃S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 197.2111

Ref: IN-DA003HYC

2-Toluenesulfonyl isocyanate

CAS: 32324-19-9

2-Toluenesulfonyl isocyanate

Purity: 95%

Color and Shape: Liquid

Molecular weight: 197.21g/mol

Ref: 54-OR938567

2-Toluenesulfonyl isocyanate

CAS: 32324-19-9

2-Toluenesulfonyl isocyanate (2TSIC) is a reactive compound that belongs to the group of polyols. It has high resistance to water and other solvents, which makes it an excellent sealant. 2TSIC reacts with hydroxy groups on polymers and monomers to form hydrogen bonds. This reaction can be used in radiation curing of sealants. 2TSIC also interacts with m1 receptors, which are proteins found in the brain and spinal cord that regulate neurotransmitter release.

Formula: C₈H₇NO₃S

Purity: Min. 95%

Color and Shape: Colourless liquid.

Molecular weight: 197.21 g/mol

Ref: 3D-FT01740

2-Methylbenzenesulfonyl Isocyanate Technical grade (~70%)

Controlled Product

CAS: 32324-19-9

Stability Moisture Sensitive
Applications 2-Methylbenzenesulfonyl Isocyanate is a reagent in the preparation of chiral hydropyrimidines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, Pu-Sheng, et al.: Angewandte Chemie, I.E., 56(50), 16032-16036 (2017)

Formula: C₈H₇NO₃S

Purity: ~70%

Color and Shape: Neat

Molecular weight: 197.21

Ref: TR-M288855