CAS 323577-36-2

L-Lysine,N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-

Description:

L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)- is a complex peptide derivative characterized by its multi-residue structure, which includes various amino acids such as lysine, arginine, proline, phenylalanine, serine, and alanine. This compound features a benzopyran moiety, which contributes to its potential biological activity, possibly influencing its interaction with biological systems. The presence of the dinitrophenyl group may enhance its reactivity and facilitate specific binding interactions. As a peptide, it is likely to exhibit properties typical of amino acids and peptides, such as solubility in polar solvents and potential bioactivity, including roles in signaling or as a substrate for enzymatic reactions. Its complex structure suggests potential applications in pharmaceuticals or biochemistry, particularly in drug design or as a research tool in studying protein interactions. However, specific biological activities and pharmacological properties would require further investigation through empirical studies.

Formula: C₆₆H₈₁N₁₅O₁₉

Synonyms:

• L-Lysine,N2-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-(9CI)
• 61: PN: WO03065997 SEQID: 91 unclaimed protein
• Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-Oh

Mca-(Ala⁷,Lys(Dnp)⁹)-Bradykinin

CAS: 323577-36-2

Substrate V, Mca-RPPGFSAFK(Dnp), is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1) a membrane-bound zinc metallopeptidase that is related to neprilysin in amino acid sequence. The kcat/Km value for the hydrolysis by ECE-1 was 1.9 x 10⁷ M⁻¹s⁻¹ and 1.7 x 10⁶ M⁻¹s⁻¹ for the hydrolysis by neprilysin. This FRET substrate was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2. Mca-RPPGFSAFK(Dnp) has also found use as substrate for insulin-degrading enzyme (IDE) and ACE2.

Formula: C₆₆H₈₁N₁₅O₁₉

Purity: 98.5%

Color and Shape: Yellow Lyophilisate

Molecular weight: 1388.46

Ref: 01-4029459

Mca-(ala7,lys(dnp)9)-bradykinin

CAS: 323577-36-2

Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1).

Formula: C₆₆H₈₁N₁₅O₁₉

Color and Shape: Solid

Molecular weight: 1388.44

Ref: TM-T78435

Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt

CAS: 323577-36-2

Please enquire for more information about Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₆₆H₈₁N₁₅O₁₉

Purity: Min. 95%

Molecular weight: 1,388.44 g/mol

Ref: 3D-FM110950