CAS 3239-45-0

(+)-Fenfluramine hydrochloride

Description:

(+)-Fenfluramine hydrochloride is a synthetic compound primarily known for its use as an appetite suppressant in the treatment of obesity. It is a member of the phenethylamine class and is characterized by its chiral nature, with the (+) designation indicating its specific optical isomer. The substance typically appears as a white to off-white crystalline powder and is soluble in water and alcohol, which facilitates its administration in pharmaceutical formulations. Its mechanism of action involves the release of serotonin, a neurotransmitter that plays a crucial role in regulating mood and appetite. However, due to concerns regarding its association with serious cardiovascular side effects, fenfluramine was withdrawn from the market in many countries. The hydrochloride salt form enhances its stability and solubility, making it suitable for various medicinal applications. As with any pharmaceutical compound, proper handling and adherence to safety guidelines are essential, given its potential effects on the central nervous system and cardiovascular health.

Formula: C₁₂H₁₆F₃N·ClH

InChI: InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m0./s1

InChI key: InChIKey=ZXKXJHAOUFHNAS-FVGYRXGTSA-N

SMILES: C([C@@H](NCC)C)C1=CC(C(F)(F)F)=CC=C1.Cl

Synonyms:

• (+)-Fenfluramine hydrochloride
• (2S)-N-Ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride (1:1)
• (S)-N-Ethyl-1-(3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride
• (S)-N-Ethyl-a-methyl-3-(trifluoromethyl)benzeneethanamine Hydrochloride
• 221-806-0
• Adifax
• Adipomin
• Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-, hydrochloride (1:?)
• Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-, hydrochloride, (S)-
• Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-, hydrochloride, (αS)-
• Dexfenfluramine hydrochloride
• Glypolix
• Isomeride
• Phenethylamine, N-ethyl-α-methyl-m-(trifluoromethyl)-, hydrochloride, (+)-
• S 5614 HCl
• S 5614 hydrochloride
• d-Fenfluramine hydrochloride
• (S)-N-Ethyl-a-methyl-m-(trifluoromethyl)phenethylamine Hydrochloride

Dexfenfluramine hydrochloride

CAS: 3239-45-0

Formula: C₁₂H₁₇ClF₃N

Molecular weight: 267.72

Ref: 7W-GP1364

(+)-Fenfluramine hydrochloride

CAS: 3239-45-0

Formula: C₁₂H₁₆F₃N·HCl

Molecular weight: 267.72

Ref: 7W-GL7092

(S)-(+)-Fenfluramine Hydrochloride

Controlled Product

CAS: 3239-45-0

Stability Hygroscopic
Applications Anorexic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pinder, et al.: Drugs, 10, 241 (1975), Caccia, S., et al.: Eur. J. Clin. Pharmacol., 29, 221 (1985), Finner, N., et al.: Curr. Ther. Res., 38, 847 (1985),

Formula: C₁₂H₁₆F₃N•HCl

Color and Shape: White To Off-White

Molecular weight: 231.263646

Ref: TR-F247596

Dexfenfluramine HCl - Bio-X ™

Controlled Product

CAS: 3239-45-0

Dexfenfluramine is a serotonin reuptake inhibitor and anorectic drug that is used in the treatment of obesity and diabetes. This drug increases the levels of serotonin in the brain by preventing its reuptake. As a result, Dexfenfluramine suppresses appetite.

Formula: C₁₂H₁₆F₃N•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 267.72 g/mol

Ref: 3D-BF164363

(S)-(+)-Fenfluramine hydrochloride

Controlled Product

CAS: 3239-45-0

(S)-(+)-Fenfluramine is a serotonin reuptake inhibitor and anorectic drug that is used in the treatment of obesity and diabetes. This drug increases the levels of serotonin in the brain by preventing its reuptake. As a result, Dexfenfluramine suppresses appetite

Formula: C₁₂H₁₇ClF₃N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 267.72 g/mol

Ref: 3D-FF23249