CAS 32452-17-8
:Guanosine tetraphosphate
Description:
Guanosine tetraphosphate, also known as GTP4 or ppGpp, is a nucleotide derivative characterized by its structure, which consists of a guanine base, a ribose sugar, and four phosphate groups. This compound plays a crucial role in cellular signaling and regulation, particularly in the context of bacterial stress responses and the stringent response, where it acts as a signaling molecule that modulates gene expression and metabolic processes. Guanosine tetraphosphate is involved in various biochemical pathways, including those related to RNA synthesis and protein synthesis regulation. Its high-energy phosphate bonds make it an important energy carrier within the cell. Additionally, it can participate in the formation of other nucleotides and nucleic acids, contributing to the overall nucleotide pool within the cell. The compound's stability and reactivity are influenced by the presence of multiple phosphate groups, which can undergo hydrolysis, releasing energy and inorganic phosphate. Overall, guanosine tetraphosphate is a vital molecule in cellular metabolism and signaling, reflecting its importance in both prokaryotic and eukaryotic organisms.
Formula:C10H17N5O17P4
InChI:InChI=1S/C10H17N5O17P4/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6(30-36(26,27)32-34(21,22)23)3(29-9)1-28-35(24,25)31-33(18,19)20/h2-3,5-6,9,16H,1H2,(H,24,25)(H,26,27)(H2,18,19,20)(H2,21,22,23)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=BUFLLCUFNHESEH-UUOKFMHZSA-N
SMILES:O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](COP(OP(=O)(O)O)(=O)O)[C@H]1OP(OP(=O)(O)O)(=O)O
Synonyms:- 5′-Diphosphoguanosine 3′-diphosphate
- Guanosine 3',5'-Bispyrophosphate
- Guanosine 3′,5′-bis(diphosphate)
- Guanosine 3′,5′-bispyrophosphate
- Guanosine 3′,5′-dipyrophosphate
- Guanosine 3′-(trihydrogen diphosphate), 5′-(trihydrogen diphosphate)
- Guanosine 3′-diphosphate 5′-diphosphate
- Guanosine 5′,3′-bisdiphosphate
- Guanosine 5′-diphosphate 3′-diphosphate
- Guanosine tetraphosphate
- Guanosine, 3',5'-Bis(Trihydrogen Diphosphate), Ion(6-)
- Guanosine, 3′,5′-bis(trihydrogen pyrophosphate)
- See more synonyms
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