CAS 32476-67-8

(3alpha,5beta,8xi,9xi)-3-[(2,6-dideoxy-3-O-methyl-beta-D-glycero-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide

Description:

The chemical substance known as (3alpha,5beta,8xi,9xi)-3-[(2,6-dideoxy-3-O-methyl-beta-D-glycero-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide, with the CAS number 32476-67-8, is a complex organic compound belonging to the class of cardenolides, which are a type of steroid glycoside. This compound features multiple hydroxyl groups, contributing to its solubility and reactivity, and a glycosidic moiety that enhances its biological activity. The presence of a cardenolide backbone suggests potential pharmacological properties, particularly in relation to cardiac function, as many cardenolides are known for their effects on the heart. The specific stereochemistry indicated by the nomenclature suggests a precise three-dimensional arrangement of atoms, which is crucial for its biological interactions. Additionally, the presence of a dideoxy sugar moiety may influence its metabolic stability and bioavailability. Overall, this compound exemplifies the intricate relationship between structure and function in bioactive natural products.

Formula: C₃₀H₄₆O₈

InChI: InChI=1/C30H46O8/c1-17-26(32)23(35-4)14-25(37-17)38-19-5-9-27(2)21-6-10-28(3)20(18-13-24(31)36-16-18)8-12-30(28,34)22(21)7-11-29(27,33)15-19/h13,17,19-23,25-26,32-34H,5-12,14-16H2,1-4H3/t17-,19?,20-,21+,22-,23+,25+,26-,27-,28-,29?,30+/m1/s1

InChI key: InChIKey=XRWQBDJPMXRDOQ-YUUDFPFBSA-N

SMILES: O[C@@]12[C@]3([C@@]([C@]4(C)[C@](O)(CC3)C[C@@H](O[C@H]5C[C@H](OC)[C@H](O)[C@@H](C)O5)CC4)(CC[C@]1(C)[C@](CC2)(C6=CC(=O)OC6)[H])[H])[H]

Periplocymarin

CAS: 32476-67-8

Periplocymarin

Purity: ≥98%

Molecular weight: 534.68g/mol

Ref: 54-BUP00875

Periplocymarin

CAS: 32476-67-8

Formula: C₃₀H₄₆O₈

Molecular weight: 534.69

Ref: 7W-GY8855

Periplocymarin

CAS: 32476-67-8

Periplocymarin, a cardiac glycoside, has potential anti-cancer activity. Octreotide-conjugated periplocymarin demonstrates tumor selectivity and may be useful as a targeting agent to improve the safety profile of cardiac glycosides for cancer therapy.

Formula: C₃₀H₄₆O₈

Purity: 95%~99%

Molecular weight: 534.69

Ref: BP-BP3656

Periplocymarin

CAS: 32476-67-8

Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.

Formula: C₃₀H₄₆O₈

Purity: 98.54% - 98.63%

Color and Shape: Solid

Molecular weight: 534.68

Ref: TM-TN2054

Periplocymarin

CAS: 32476-67-8

Periplocymarin is a cardiac glycoside, which is primarily sourced from the plant genus Periploca. This compound functions by inhibiting the Na⁺/K⁺-ATPase pump, leading to an increase in intracellular sodium. This sodium buildup consequently results in enhanced calcium ion concentrations through the sodium-calcium exchanger, thereby strengthening myocardial contractions.

Formula: C₃₀H₄₆O₈

Purity: Min. 95%

Molecular weight: 534.7 g/mol

Ref: 3D-HBA47667