CAS 324763-46-4

(3S,5S)-5-[(1S,3S)-1-Azido-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]dihydro-3-(1-methylethyl)-2(3H)-furanone

Description:

The chemical substance with the name "(3S,5S)-5-[(1S,3S)-1-Azido-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]dihydro-3-(1-methylethyl)-2(3H)-furanone" and CAS number "324763-46-4" is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a furanone core, which is a cyclic compound containing a lactone and is known for its potential biological activity. The presence of an azido group indicates potential for reactivity, particularly in click chemistry applications. Additionally, the compound contains multiple methoxy groups and a branched alkyl chain, which may influence its solubility and interaction with biological systems. The stereochemical configuration (3S,5S) and (1S,3S) suggest that the compound may exhibit specific spatial arrangements that could affect its pharmacological properties. Overall, this compound's unique structure may make it of interest in medicinal chemistry and drug development, particularly for targeting specific biological pathways or mechanisms.

Formula: C₂₅H₃₉N₃O₅

InChI: InChI=1/C25H39N3O5/c1-16(2)19(14-21(27-28-26)23-15-20(17(3)4)25(29)33-23)12-18-8-9-22(31-6)24(13-18)32-11-7-10-30-5/h8-9,13,16-17,19-21,23H,7,10-12,14-15H2,1-6H3/t19-,20-,21-,23-/m0/s1

InChI key: InChIKey=YTRPFWMXDNQTCX-FKEBYFGASA-N

SMILES: [C@@H](C[C@H](CC1=CC(OCCCOC)=C(OC)C=C1)C(C)C)(N=[N+]=[N-])[C@@]2(C[C@@H]([C@H](C)C)C(=O)O2)[H]

Synonyms:

• (3S,5S)-5-((1S,3S)-1-azido-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one
• (3S,5S)-5-((1S,3S)-3-(3-(3-methoxypropoxy)-4-methoxybenzyl)-1-azido-4-methylpentyl)-dihydro-3-isopropylfuran-2(3H)-one
• (3S,5S)-5-[(1S,3S)-1-azido-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]dihydro-3-(1-methylethyl)-2(3H)-Furanone
• (3S,5S)-5-{(1S,3S)-1-azido-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-Methylpentyl}-3-(propan-2-yl)dihydrofuran-2(3H)-one
• (3S,5S)-5-{(1S,3S)-1-azido-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}-3-(1-methylethyl)dihydrofuran-2(3H)-one
• 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one
• 5-[(1S,3S)-1-azido-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]dihydro-3-(1-methylethyl)-,(3S,5S)-2(3H)-Furanone
• 2(3H)-Furanone, 5-[(1S,3S)-1-azido-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]dihydro-3-(1-methylethyl)-, (3S,5S)-
• 2(3H)-Furanone, 5-[(1S,3S)-1-azido-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methylpentyl]d
• (3S,5S)-5-{(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one
• aliskireninterMediatebearing

5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one

CAS: 324763-46-4

Formula: C₂₅H₃₉N₃O₅

Ref: TR-TRC-A850300

5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one

Controlled Product

CAS: 324763-46-4

Applications 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one is an intermediate in the preparation of orally active renin inhibitor Aliskiren (A536000).
References Wu, Y. et al.: Zhong. Yao. Dax. Xueb., 42, 400 (2011); Rueger, H. et al.: Tetrahed. Lett., 41, 10085 (2000);

Formula: C₂₅H₃₉N₃O₅

Color and Shape: Neat

Molecular weight: 461.59

Ref: TR-A850300