CAS 32479-73-5

1,3-diethylbarbituric acid

Description:

1,3-Diethylbarbituric acid is a chemical compound belonging to the barbiturate class, which are derivatives of barbituric acid. It is characterized by the presence of two ethyl groups attached to the nitrogen atoms at positions 1 and 3 of the barbituric acid structure. This compound typically appears as a white crystalline solid and is soluble in water and organic solvents, reflecting its polar nature due to the carboxylic acid functional group. 1,3-Diethylbarbituric acid exhibits sedative and hypnotic properties, similar to other barbiturates, and has been studied for its effects on the central nervous system. Its pharmacological activity is attributed to its ability to enhance the action of gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission. Due to its potential for abuse and dependence, the use of barbiturates, including 1,3-diethylbarbituric acid, is highly regulated in many countries. Safety and handling precautions are essential when working with this compound, as it can pose health risks if misused.

Formula: C₈H₁₂N₂O₃

InChI: InChI=1S/C8H12N2O3/c1-3-9-6(11)5-7(12)10(4-2)8(9)13/h3-5H2,1-2H3

InChI key: InChIKey=XUCMDLYIYOXEBF-UHFFFAOYSA-N

SMILES: C(C)N1C(=O)N(CC)C(=O)CC1=O

Synonyms:

• 1,3-Diethyl-1,3-diazinane-2,4,6-trione
• 1,3-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
• 1,3-Diethyl-2-oxobarbituric acid
• 1,3-diethylpyrimidine-2,4,6(1H,3H,5H)-trione
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-diethyl-
• Barbituric acid, 1,3-diethyl-
• N,N′-Diethylbarbituric acid
• 1,3-Diethylbarbituric acid
• Itraphylline impuritieAQ

1,3-Diethylpyrimidine-2,4,6(1H,3H,5H)-trione

CAS: 32479-73-5

1,3-Diethylpyrimidine-2,4,6(1H,3H,5H)-trione

Purity: ≥95%

Molecular weight: 184.19g/mol

Ref: 54-OR24889

1,3-Diethylbarbituric Acid

Controlled Product

CAS: 32479-73-5

Applications 1,3-Diethylbarbituric Acid can be used as reactant/reagent in green preparation of spiropyran derivatives via three-component cyclization of indantrione with active methylene compounds and cyclic diketones in the presence of compact fluorescent lamp.
References Rai, P., et al.: ChemistrySelect, 1, 4450 (2016)

Formula: C₈H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 184.192

Ref: TR-D444875