CAS 325965-23-9

5-[(2S)-1,2,3,6-Tetrahydro-5-(4-morpholinylmethyl)-2-pyridinecarboxylic acid]pristinamycin IA

Description:

5-[(2S)-1,2,3,6-Tetrahydro-5-(4-morpholinylmethyl)-2-pyridinecarboxylic acid]pristinamycin IA is a complex organic compound that belongs to the class of antibiotics known as streptogramins. It is derived from the natural product pristinamycin, which is produced by the bacterium *Streptomyces pristinaespiralis*. This compound exhibits a unique structure characterized by a bicyclic system and a morpholine moiety, contributing to its biological activity. It functions primarily by inhibiting bacterial protein synthesis, making it effective against a range of Gram-positive bacteria, including some strains resistant to other antibiotics. The stereochemistry of the compound is significant, as the (2S) configuration plays a crucial role in its interaction with bacterial ribosomes. Additionally, its solubility and stability can be influenced by the presence of functional groups, such as the carboxylic acid and morpholine, which may also affect its pharmacokinetic properties. Overall, this compound represents a valuable tool in the fight against bacterial infections, particularly in cases where conventional treatments may fail.

Formula: C₅₀H₆₃N₉O₁₀

Synonyms:

• RPR-202868
• N-(3-Hydroxypyridin-2-ylcarbonyl)-L-threonyl-D-(2-aminobutyryl)-L-prolyl-L-N-methyl-[4-(N,N-dimethylamino)]phenylalanyl-L-[5-(morpholin-4-ylmethyl)-1,2,3,6-tetrahydropyridin-2(S)-ylcarbonyl]-2-phenyl-L-glycine C-1.6-O-3.1-lactone

Linopristin

CAS: 325965-23-9

Linopristin is a streptogramin B class antibiotic. It is one of the components of the antibiotic combination NXL103.

Formula: C₅₀H₆₃N₉O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 950.09

Ref: TM-T25740