CAS 3262-72-4

BOC-L-serine

Description:

BOC-L-serine, also known as tert-butyloxycarbonyl-L-serine, is a derivative of the amino acid serine, characterized by the presence of a tert-butyloxycarbonyl (BOC) protecting group. This compound is commonly used in peptide synthesis to protect the amino group of serine, facilitating the formation of peptide bonds without interference from the amino group. BOC-L-serine is typically a white to off-white crystalline solid, and it is soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO), but less soluble in water. The BOC group can be removed under acidic conditions, allowing for the regeneration of the free amino group for further reactions. Its molecular structure includes a hydroxyl group, which contributes to its reactivity and ability to participate in various biochemical processes. BOC-L-serine is utilized in research and pharmaceutical applications, particularly in the synthesis of peptides and other bioactive compounds. Proper handling and storage are essential, as with many chemical substances, to maintain stability and prevent degradation.

Formula: C₈H₁₅NO₅

InChI: InChI=1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1

InChI key: InChIKey=FHOAKXBXYSJBGX-YFKPBYRVSA-N

SMILES: [C@@H](NC(OC(C)(C)C)=O)(C(O)=O)CO

Synonyms:

• (2S)-2-[(tert-butoxycarbonyl)amino]-3-hydroxypropanoate
• (2S)-2-[[(tert-Butoxy)carbonyl]amino]-3-hydroxypropanoic acid
• (2S)-3-Hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
• (S)-2-(tert-Butoxycarbonylamino)-3-hydroxypropanoic acid
• (S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropionic acid
• <span class="text-smallcaps">L</span>-N-tert-Butoxycarbonylserine
• <span class="text-smallcaps">L</span>-Serine, N-[(1,1-dimethylethoxy)carbonyl]-
• BOC-<span class="text-smallcaps">L</span>-serine
• BOC-Serine
• Boc-L-Ser-OH
• Boc-Ser-OH
• N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-serine
• N-(tert-Butoxycarbonyl)-L-serine
• N-(tert-butoxycarbonyl)serine
• N-BOC-<span class="text-smallcaps">L</span>-serine
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-serine
• N-t-Butoxycarbonylserine
• N-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-serine
• N-tert-Butyloxycarbonylserine
• NSC 164056
• Serine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-
• N-tert-Butyloxycarbonyl-L-serine
• Serine, N-carboxy-, N-tert-butyl ester, L-
• N-[(1,1-Dimethylethoxy)carbonyl]-L-serine

N-(tert-Butoxycarbonyl)-L-serine

CAS: 3262-72-4

Formula: C₈H₁₅NO₅

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 205.21

Ref: 3B-B1637

N-Boc-L-serine, 98% (dry wt.), may cont. up to 10% water

CAS: 3262-72-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₅NO₅

Purity: 98%

Color and Shape: White, Powder or crystalline powder

Molecular weight: 205.21

Ref: 02-A16224

Boc-Ser-OH Bachem Quality Grade

CAS: 3262-72-4

Educt for the synthesis of Boc-Ser β-lactone, a useful synthon for obtaining stereochemically pure β-substituted α-amino acids. Building block for the incorporation of O-acyl isopeptide bonds during Fmoc-SPPS.

Formula: C₈H₁₅NO₅

Purity: > 99%

Color and Shape: White

Molecular weight: 205.21

Ref: 01-4001097

Serine, N-[(1,1-dimethylethoxy)carbonyl]-

CAS: 3262-72-4

Formula: C₈H₁₅NO₅

Purity: 96%

Color and Shape: Solid

Molecular weight: 205.2084

Ref: IN-DA00I679

Boc-Ser-OH

CAS: 3262-72-4

Formula: C₈H₁₅NO₅

Molecular weight: 205.21

Ref: 7W-GM6224

L-Serine-2,3,3-d3-N-t-BOC

CAS: 3262-72-4

Formula: HOCD₂CD(NHtBOC)COOH

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 208.22

Ref: 3U-D6619

(2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid

CAS: 3262-72-4

(2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid

Formula: C₈H₁₅NO₅

Purity: 96%

Color and Shape: white solid

Molecular weight: 205.2084g/mol

Ref: 54-OR18040

Boc-L-serine

CAS: 3262-72-4

Boc-L-serine is a cyclic peptide that contains a hydroxyl group and a trifluoroacetate group. It has been shown to have anticancer activity in experimental models, but the mechanism of action is not fully understood. Boc-L-serine inhibits the growth of cancer cells by binding to P2Y receptors and blocking the downstream signaling cascade. This drug also has been shown to be stereospecific with respect to its biological activity, which may be due to hydrogenation of nitrogen atoms on the molecule.

Formula: C₈H₁₅NO₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 205.21 g/mol

Ref: 3D-FB47088

Boc-Ser-OH

CAS: 3262-72-4

M03318 - Boc-Ser-OH

Formula: C₈H₁₅NO₅

Purity: 95%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 205.21

Ref: 10-M03318

BOC-L-Serine extrapure, 99%

CAS: 3262-72-4

Formula: C₈H₁₅NO₅

Purity: min. 99.0%

Color and Shape: White, Crystalline powder

Molecular weight: 205.20

Ref: SR-77874

N-Boc-L-Serine

Controlled Product

CAS: 3262-72-4

Applications N-Boc-L-serine is an N-Boc-protected form of L-Serine (S270975). L-Serine is a nonessential amino acid that is required for the synthesis of sphingolipids and phosphatidylserine, compounds that are important for central nervous system neuronal survival. L-Serine is also important in intermediary metabolism in eukaryotic cells.
References de Koning, T., et al.: Biochem. J., 371, 653 (2003); Furuya, S.: Asia Pac. J. Clin. Nutr., 17, 312 (2008); Hirabayashi, Y. & Furuya, S.: Prog. Lipid. Res., 47, 188 (2008)

Formula: C₈H₁₅NO₅

Color and Shape: Neat

Molecular weight: 205.21

Ref: TR-B667355

N-Boc-L-Serine

CAS: 3262-72-4

Formula: C₈H₁₅NO₅

Molecular weight: 205.21

Ref: ST-EA-CP-L8036