CAS 32634-68-7

(+)-Di-p-toluoyl-D-tartaric acid

Description:

(+)-Di-p-toluoyl-D-tartaric acid, with the CAS number 32634-68-7, is a chiral organic compound primarily used in asymmetric synthesis and as a resolving agent for racemic mixtures. This compound is a derivative of tartaric acid, featuring two p-toluoyl groups attached to the hydroxyl groups of the tartaric acid backbone. It is characterized by its ability to form stable diastereomeric salts with various amines, which facilitates the separation of enantiomers. The compound is typically a white to off-white crystalline solid, exhibiting good solubility in organic solvents such as ethanol and acetone, while being less soluble in water. Its chirality and structural features contribute to its utility in the pharmaceutical industry, particularly in the development of chiral drugs. Additionally, (+)-Di-p-toluoyl-D-tartaric acid is known for its relatively high melting point and specific optical rotation, which are indicative of its purity and enantiomeric excess. Overall, this compound plays a significant role in stereochemistry and the synthesis of optically active compounds.

Formula: C₂₀H₁₈O₈

InChI: InChI=1/C18H18O6/c1-11-3-7-13(8-4-11)23-15(17(19)20)16(18(21)22)24-14-9-5-12(2)6-10-14/h3-10,15-16H,1-2H3,(H,19,20)(H,21,22)

InChI key: InChIKey=CMIBUZBMZCBCAT-HOTGVXAUSA-N

SMILES: [C@@H]([C@H](OC(=O)C1=CC=C(C)C=C1)C(O)=O)(OC(=O)C2=CC=C(C)C=C2)C(O)=O

Synonyms:

• (+)-Bis-O,O′-(4-toluoyl)-<span class="text-smallcaps">D</span>-tartrate
• (+)-Di-O,O′-p-toluoyltartaric acid
• (+)-Di-O,O′-p-toluyltartaric acid
• (+)-Di-O-(p-toluoyl)tartaric acid
• (+)-Di-O-p-toluoyl-<span class="text-smallcaps">D</span>-tartaric acid
• (+)-Di-p-toluoyl-<span class="text-smallcaps">D</span>-tartaric acid
• (+)-Di-p-toluoyl-D-tartaric acid
• (+)-Di-p-toluoyl-D-tartaric acid(Anhydrous)
• (+)-Di-p-toluoyltartaric acid
• (+)-Ditoluoyltartaric acid
• (+)-O,O-Di-p-toluoyltartaric acid
• (+)-O,O′-Di-p-toluoyl-<span class="text-smallcaps">D</span>-tartaric acid
• (-)-di-p-Toluyl-L-tartaric acid
• (2S,35)-(-)-di-o-4-Toluoyl-D-tartaric acid
• (2S,3S)-(+)-Di-p-toluoyltartaric acid
• (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]succinic acid
• (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid
• (S,S)-O,O′-Di-p-toluoyltartaric acid
• 2,3-Bis(4-Methylphenoxy)Butanedioic Acid
• 2,3-Bis[(4-Methylbenzoyl)Oxy]-,[S-(Theta,Theta)]-Butanedioicaci
• 2,3-Bis[(4-methylbenzoyl)oxy]succinic acid
• 2,3-Bis{[(4-Methylphenyl)Carbonyl]Oxy}Butanedioic Acid Hydrate
• 2,3-Di-O-Para-Toluoyl-D-Tartaricacidhydrate
• 2,3-Di-O-para-toluoyl-D-tartaric acid
• <span class="text-smallcaps">D</span>-Bis(O-4-methylbenzoyl)tartaric acid
• <span class="text-smallcaps">D</span>-Di-O,O′-p-toluyltartaric acid
• <span class="text-smallcaps">D</span>-Di-p-toluoyltartaric acid
• Butanedioic acid, 2,3-bis((4-methylbenzoyl)oxy)-, (2S,3S)-
• Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [S-(R*,R*)]-
• D-Dtta
• Di-p-toluoyl-l-tartaric acid
• L-di-p-Toluyltartaric acid
• NSC 97592
• Tartaric acid, di-p-toluate, (+)-
• p-Toluic acid, diester with <span class="text-smallcaps">D</span>-tartaric acid
• p-Toluic acid, diester with D-tartaric acid
• D-PTTA
• O,O'-DI-P-TOLUOYL-D-TARTARIC ACID
• (+)-DI-P-TOLUOYL-D-TRATARIC ACID
• D-(+)-DI-P-TOLUOYL TARTARIC ACID
• D-(+)-TARTARIC ACID DI-4-TOLUOYL ESTER
• (+)-DTTA
• O,O'-DI-TOLUOYL-D-(+)-TARTARIC ACID
• D-(+)-TARTARIC ACID-O,O'-DI-P-TOLUOYL ESTER
• (+)-O,O'-DI-P-TOLUOYL-D-TARTARIC ACID
• (+)-DI-O,O'-P-TOLUYL-D-TARTARIC ACID
• DI-O-4-TOLUOYL-D-TARTARIC ACID
• (+)-DI-1,4-TOLUOYL-D-TARTARIC ACID
• (2S,3S)-2,3-BIS-(4-METHYL-BENZOYLOXY)-SUCCINIC ACID
• DI-(4-METHYL)BENZOYL-D-TARTARIC ACID
• L-(-)-DI-P-TOLUOYL-D-TARTARIC ACID

(+)-Di-p-toluoyl-D-tartaric Acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 386.36

Ref: 3B-D1417

(+)-Di-p-toluoyl-D-tartaric acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purity: 98%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 386.356

Ref: 10-F011666

Di-p-toluoyl-D-tartaric acid, 98%

CAS: 32634-68-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₀H₁₈O₈

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to off-white

Molecular weight: 386.36

Ref: 02-L13223

Rivastigmine Related Compound A ((+)-Di-(p-toluoyl)-D-tartaric acid)

CAS: 32634-68-7

Salts and esters of tartaric acid

Formula: C₂₀H₁₈O₈

Color and Shape: Powder

Molecular weight: 386.10017

Ref: 45-1604869

Di-p-toluoyl-D-tartaric Acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 386.3521

Ref: IN-DA0032AX

Rivastigmine USP Related Compound A

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Color and Shape: White To Off-White Solid

Molecular weight: 386.36

Ref: 4Z-R-0720

(2S,3S)-(+)-2,3-Bis[(4-methylbenzoyl)oxy]butane-1,4-dioic acid

CAS: 32634-68-7

(2S,3S)-(+)-2,3-Bis[(4-methylbenzoyl)oxy]butane-1,4-dioic acid

Formula: C₂₀H₁₈O₈

Purity: 99%

Color and Shape: white crystalline powder

Molecular weight: 386.35g/mol

Ref: 54-OR14900

Di-p-toluoyl-D-tartaric acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 386.36

Ref: 7W-GK4062

(+)-Di-p-toluoyl-D-(+)-tartaric Acid

CAS: 32634-68-7

Color and Shape: Neat

Ref: 86-MM1497.03

(+)-O,O'-Di-p-toluoyl-D-tartaric acid

CAS: 32634-68-7

(+)-O,O'-Di-p-toluoyl-D-tartaric acid is a potent and selective ligand for the dopamine D2 receptor. It was first synthesized in 1968 and has been extensively studied for its interactions with dopamine receptors. (+)-O,O'-Di-p-toluoyl-D-tartaric acid has been shown to be an orthosteric agonist at the D2 receptor, meaning it binds directly to the receptor in the absence of any other compounds. It binds to the extracellular site of the receptor, with a binding affinity that is 10 times more potent than that of apomorphine. The compound has been shown to have antidepressant effects when administered systemically, as well as in animal models of depression. This activity may be due to its ability to selectively activate dopamine D2 receptors in regions such as the prefrontal cortex.

Formula: C₂₀H₁₈O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 386.35 g/mol

Ref: 3D-FD22531

(+)-O,O’-Di-p-toluoyl-D-tartaric Acid

CAS: 32634-68-7

Impurity Rivastigmine USP Related Compound A
Applications Inhibitor of enzyme. Rivastigmine USP Related Compound A.
References Olsen,L., et al.: Bioorg. Med. Chem., 14, 2627 (2007),

Formula: C₂₀H₁₈O₈

Color and Shape: Neat

Molecular weight: 386.35

Ref: TR-D494380

Rivastigmine USP Related Compound A

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Molecular weight: 386.37

Ref: ST-EA-CP-R27038