CAS 327056-26-8

Benzonitrile, 3-fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]-

Description:

Benzonitrile, 3-fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]- is a chemical compound characterized by its complex structure, which includes a benzonitrile moiety and a substituted oxadiazole ring. This compound features multiple functional groups, including a nitrile group (-C≡N) and a fluorine atom, which can influence its reactivity and physical properties. The presence of the pyridine ring contributes to its potential biological activity, making it of interest in pharmaceutical research. Typically, compounds like this may exhibit properties such as moderate to high solubility in organic solvents, and their melting and boiling points can vary based on the specific substituents and their interactions. Additionally, the fluorine atoms can enhance lipophilicity and metabolic stability, which are important factors in drug design. Overall, the unique combination of functional groups in this compound suggests potential applications in medicinal chemistry, particularly in the development of new therapeutic agents.

Formula: C₁₄H₆F₂N₄O

AZD 9272

CAS: 327056-26-8

AZD 9272

Purity: ≥95%

Molecular weight: 284.22g/mol

Ref: 54-BUP09042

AZD 9272

Controlled Product

CAS: 327056-26-8

Applications AZD 9272 is a potent and selective nervous system penetrant mGlu5 antagonist showing psychoactive and psychomimetic effects.
References Swedberg, M. et al.: J. Pharmacol. Exp. Ther., 350, 212 (2014);

Formula: C₁₄H₆F₂N₄O

Color and Shape: Neat

Molecular weight: 284.22

Ref: TR-A808175

AZD 9272

CAS: 327056-26-8

AZD 9272 is a small molecule drug that binds to the m1 muscarinic receptor and allosteric modulates its activity. It also selectively binds to other muscarinic receptors, such as M3 and M5. In vitro studies have shown that AZD 9272 has a high binding affinity for the m1 receptor and inhibits acetylcholine-induced activation of the receptor. The compound may be a potential drug target for the treatment of cognitive disorders such as Alzheimer's disease.

Formula: C₁₄H₆F₂N₄O

Purity: Min. 95%

Molecular weight: 284.22 g/mol

Ref: 3D-CNA05626

AZD 9272

CAS: 327056-26-8

AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.

Formula: C₁₄H₆F₂N₄O

Purity: 98.29%

Color and Shape: Solid

Molecular weight: 284.22

Ref: TM-T14389