CAS 32779-36-5

5-Bromo-2-chloropyrimidine

Description:

5-Bromo-2-chloropyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with both bromine and chlorine atoms. The presence of these halogen substituents at the 5 and 2 positions, respectively, contributes to its reactivity and potential applications in various chemical reactions, particularly in the synthesis of pharmaceuticals and agrochemicals. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. It is soluble in organic solvents such as ethanol and dichloromethane but has limited solubility in water. The compound exhibits moderate toxicity, necessitating careful handling and appropriate safety measures during use. Its unique structure allows it to participate in nucleophilic substitution reactions, making it a valuable intermediate in organic synthesis. Additionally, 5-bromo-2-chloropyrimidine can serve as a building block for the development of biologically active molecules, highlighting its significance in medicinal chemistry.

Formula: C₄H₂N₂BrCl

InChI: InChI=1/C4H2BrClN2/c5-3-1-7-4(6)8-2-3/h1-2H

SMILES: c1c(cnc(Cl)n1)Br

Synonyms:

• 2-Chloro-5-Bromopyrimidine
• Pyrimidine, 5-bromo-2-chloro-
• Majorimpurityis
• 2C5Bp

5-Bromo-2-chloropyrimidine, 98+%

CAS: 32779-36-5

It is applied as a pharmaceutical intermediate, in the synthesis of pharmaceutical goods such as inhibitors. It is also employed in the cross-coupling reactions of indium organometallics with 2,5-dihalopyrimidines. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar

Formula: C₄H₂BrClN₂

Purity: 98+%

Color and Shape: Crystals or crystalline powder, White to cream

Molecular weight: 193.43

Ref: 02-L18360

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Formula: C₄H₂BrClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 193.4291

Ref: IN-DA00347L

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Formula: C₄H₂BrClN₂

Molecular weight: 193.43

Ref: 7W-GK1617

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

5-Bromo-2-chloropyrimidine

Formula: C₄H₂BrClN₂

Purity: 98%

Color and Shape: light yellow solid

Molecular weight: 193.43g/mol

Ref: 54-OR3560

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Formula: C₄H₂BrClN₂

Purity: >97.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 193.43

Ref: 3B-B2847

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Purity: 98%

Molecular weight: 193.43

Ref: FT-B1216

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Formula: C₄H₂BrClN₂

Purity: 98.0%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 193.43

Ref: 10-F023429

Macitentan Impurity 20

CAS: 32779-36-5

Formula: C₄H₂BrClN₂

Molecular weight: 193.43

Ref: 4Z-M-128025

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Intermediate in the synthesis of macitentan; building block

Formula: C₄H₂BrClN₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 193.43 g/mol

Ref: 3D-FB11177

5-Bromo-2-chloropyrimidine-15N2

Controlled Product

CAS: 32779-36-5

Formula: C₄H₂BrCl₁₅N₂

Color and Shape: Neat

Molecular weight: 195.416

Ref: TR-B682297

5-Bromo-2-chloropyrimidine

Controlled Product

CAS: 32779-36-5

Stability Hygroscopic
Applications 5-Bromo-2-chloropyrimidine is an intermediate in the synthesis of pharmaceutical goods such as inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Venier, O., et al.: Bioorg. Med. Chem. Lett., 23, 2414 (2013); Zhang, Z.H., et al.: J. Med. Chem., 56, 568 (2013);

Formula: C₄H₂BrClN₂

Color and Shape: Neat

Molecular weight: 193.43

Ref: TR-B682295

5-Bromo-2-chloropyrimidine

CAS: 32779-36-5

Formula: C₄H₂BrClN₂

Molecular weight: 193.43

Ref: ST-EA-CP-M5010