CAS 32797-92-5

Glisentide

Description:

Glisentide, with the CAS number 32797-92-5, is a chemical compound that belongs to the class of sulfonylureas, which are primarily used in the management of type 2 diabetes. This substance functions as an antihyperglycemic agent, promoting insulin secretion from pancreatic beta cells and thereby helping to lower blood glucose levels. Glisentide is characterized by its ability to enhance the sensitivity of peripheral tissues to insulin, contributing to improved glucose uptake. The compound typically exhibits moderate solubility in water and is stable under standard conditions. Its pharmacological profile includes a relatively long duration of action, making it suitable for once-daily dosing in clinical settings. As with other sulfonylureas, potential side effects may include hypoglycemia and weight gain, necessitating careful monitoring of patients. Overall, Glisentide represents an important option in the therapeutic arsenal for diabetes management, although its use should be tailored to individual patient needs and conditions.

Formula: C₂₂H₂₇N₃O₅S

InChI: InChI=1S/C22H27N3O5S/c1-30-20-9-5-4-8-19(20)21(26)23-15-14-16-10-12-18(13-11-16)31(28,29)25-22(27)24-17-6-2-3-7-17/h4-5,8-13,17H,2-3,6-7,14-15H2,1H3,(H,23,26)(H2,24,25,27)

InChI key: InChIKey=NSJYMFYVNWVGON-UHFFFAOYSA-N

SMILES: C(NCCC1=CC=C(S(NC(NC2CCCC2)=O)(=O)=O)C=C1)(=O)C3=C(OC)C=CC=C3

Synonyms:

• N-[2-[4-[[[(Cyclopentylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide
• Benzamide, N-[2-[4-[[[(cyclopentylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-
• N-[p-[β-(o-Anisoylamino)ethyl]phenylsulfonyl]-N′-cyclopentylurea
• Urea, 1-[[p-(2-o-anisamidoethyl)phenyl]sulfonyl]-3-cyclopentyl-
• Su 661

Glipentide

CAS: 32797-92-5

Glieptide, a second-generation sulfonylurea, promotes the accumulation of fructose 2, 6-diphosphate in liver cells.

Formula: C₂₂H₂₇N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 445.53

Ref: TM-TP2383