CAS 328-67-6

3-Bromo-5-(trifluoromethyl)benzoic acid

Description:

3-Bromo-5-(trifluoromethyl)benzoic acid is an aromatic carboxylic acid characterized by the presence of a bromine atom and a trifluoromethyl group attached to a benzene ring. The bromine substituent is located at the meta position relative to the carboxylic acid group, while the trifluoromethyl group is positioned at the para position. This compound is typically a white to off-white solid at room temperature and is known for its relatively high melting point. It is soluble in organic solvents such as acetone and dichloromethane but has limited solubility in water due to the hydrophobic nature of the trifluoromethyl group. The presence of both bromine and trifluoromethyl groups contributes to its unique chemical reactivity, making it useful in various synthetic applications, including pharmaceuticals and agrochemicals. Additionally, the compound exhibits potential biological activity, which may be explored in medicinal chemistry. Proper handling and safety precautions are essential due to its potential toxicity and environmental impact.

Formula: C₈H₄BrF₃O₂

InChI: InChI=1/C8H4BrF3O2/c9-6-2-4(7(13)14)1-5(3-6)8(10,11)12/h1-3H,(H,13,14)

SMILES: c1c(cc(cc1C(F)(F)F)Br)C(=O)O

Synonyms:

• Bromotrifluoromethylbenzoic acid
• Benzoic acid, 3-bromo-5-(trifluoromethyl)-
• 3-Bromo-5-trifluoromethyl-benzoic acid

Benzoic acid, 3-bromo-5-(trifluoromethyl)-

CAS: 328-67-6

Formula: C₈H₄BrF₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 269.0154

Ref: IN-DA00I698

3-Bromo-5-(trifluoromethyl)benzoic Acid

CAS: 328-67-6

Formula: C₈H₄BrF₃O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 269.02

Ref: 3B-B4533

3-Bromo-5-(trifluoromethyl)benzoic acid

CAS: 328-67-6

3-Bromo-5-(trifluoromethyl)benzoic acid

Formula: C₈H₄BrF₃O₂

Purity: 97%

Color and Shape: white solid

Molecular weight: 269.02g/mol

Ref: 54-PC7295

3-Bromo-5-(trifluoromethyl)benzoic acid

CAS: 328-67-6

Formula: C₈H₄BrF₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 269.017

Ref: 10-F045058

3-Bromo-5-(trifluoromethyl)benzoic acid

CAS: 328-67-6

3-Bromo-5-(trifluoromethyl)benzoic acid is a drug resistant hydroxamic acid that can be used to treat tuberculosis. 3-Bromo-5-(trifluoromethyl)benzoic acid inhibits the growth of Mycobacterium tuberculosis and has been shown to be effective against multi-drug resistant strains of Mycobacterium tuberculosis. 3-Bromo-5-(trifluoromethyl)benzoic acid has also been shown to inhibit the synthesis of proteins by blocking the production of amino acids. The drug blocks protein synthesis by inhibiting an enzyme called hydroxamate methyltransferase, which is responsible for converting N5,N10-methylenetetrahydrofolate into 5,10 methylenetetrahydrofolate (an important cofactor in protein synthesis).

Formula: C₈H₄BrF₃O₂

Purity: Min. 95%

Molecular weight: 269.02 g/mol

Ref: 3D-FB64188