CAS 328-90-5
:2-Hydroxy-4-(trifluoromethyl)benzoic acid
Description:
2-Hydroxy-4-(trifluoromethyl)benzoic acid, also known as TFBA, is an aromatic carboxylic acid characterized by the presence of a hydroxyl group and a trifluoromethyl group on a benzene ring. Its molecular formula is C8H5F3O3, and it features a benzoic acid structure with a hydroxyl (-OH) group at the ortho position and a trifluoromethyl (-CF3) group at the para position. This compound is typically a white crystalline solid and is soluble in organic solvents, with limited solubility in water. The trifluoromethyl group imparts unique electronic properties, enhancing its acidity and making it a useful intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Additionally, TFBA can exhibit interesting biological activities, making it a subject of research in medicinal chemistry. Its stability under various conditions and reactivity with nucleophiles further contribute to its utility in synthetic applications. Safety precautions should be observed when handling this compound due to its potential toxicity and environmental impact.
Formula:C8H5F3O3
InChI:InChI=1S/C8H5F3O3/c9-8(10,11)4-1-2-5(7(13)14)6(12)3-4/h1-3,12H,(H,13,14)
InChI key:InChIKey=XMLFPUBZFSJWCN-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C1=CC(O)=C(C(O)=O)C=C1
Synonyms:- 2,4-Cresotic acid, α,α,α-trifluoro-
- 2-Hydroxy-4-(Trifluoromethyl)Benzoic Acid
- 2-Hydroxy-4-Trifluoromethylbenzoic Acid
- 4-(Trifluoromethy)Salicylic Acid
- 4-(Trifluoromethyl)-2-Hydroxybenzoic Acid
- 4-Trifluoromethyl Salicylic Acid
- 4-Trifluoromethylsalicylic Acid
- 4-Trifluoromethylsalicylicacid
- Benzoic Acid, 2-Hydroxy-4-(Trifluoromethyl)-
- P-Trifluoromethylsalicylicacid
- Rarechem Al Be 1424
- Trifluoromethylsalicylicacid
- p-(Trifluoromethyl)salicylic acid
- See more synonyms
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Found 10 products.
4-(Trifluoromethyl)salicylic Acid
CAS:Formula:C8H5F3O3Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:206.124-Trifluoromethylsalicylic acid
CAS:Formula:C8H5F3O3Purity:97%Color and Shape:SolidMolecular weight:206.1187Triflusal EP Impurity B
CAS:Controlled ProductFormula:C8H5F3O3Color and Shape:NeatMolecular weight:206.122-Hydroxy-4-(trifluoromethyl)benzoic acid
CAS:<p>2-Hydroxy-4-(trifluoromethyl)benzoic acid</p>Formula:C8H5F3O3Purity:98%Color and Shape: white powderMolecular weight:206.12g/molTriflusal EP Impurity B-d3 (Desacetyl Triflusalic Acid-d3)
CAS:Formula:C8H2F3O3D3Molecular weight:209.14Desacetyl Triflusal
CAS:<p>Applications The active metabolite of Triflusal; inhibits cardiac hypertrophy in vitro and in vivo by blocking the NF-κB signaling pathway.<br>References Bayon, Y., et al.: Br. J. Pharmacol., 126, 1359 (1999), Cabrero, A., et al.: Diabetes, 50, 1883 (2001), Cabrero, A., et al.: J. Biol. Chem., 277, 10100 (2002), Culebras, A., et al.: Neurology, 62, 1073 (2004),<br></p>Formula:C8H5F3O3Color and Shape:NeatMolecular weight:206.12Desacetyl triflusal
CAS:<p>Triflusal is a drug that inhibits the production of colony-stimulating factor and energy metabolism. It has been shown to have beneficial effects on the liver in vivo. Triflusal also has a chemoattractant protein activity that may be useful for tumor therapy. The pharmacological treatment of triflusal is associated with an increased risk of cancer in humans, which can be attributed to its irreversible inhibition of cyclin D2. Triflusal may have therapeutic potential for treating pain and inflammation, but its use should be limited to patients at low risk for cancer.</p>Formula:C8H5F3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:206.12 g/mol4-(Trifluoromethyl)salicylic acid
CAS:Formula:C8H5F3O3Purity:97%Color and Shape:SolidMolecular weight:206.12
