CAS 328-93-8

2,5-bis(trifluoromethyl)aniline

Description:

2,5-Bis(trifluoromethyl)aniline, with the CAS number 328-93-8, is an organic compound characterized by the presence of two trifluoromethyl groups attached to the aniline structure. This compound features a benzene ring with an amino group (-NH2) and two trifluoromethyl groups (-CF3) located at the 2 and 5 positions. The trifluoromethyl groups significantly enhance the compound's lipophilicity and can influence its electronic properties, making it a useful intermediate in the synthesis of various pharmaceuticals and agrochemicals. 2,5-Bis(trifluoromethyl)aniline is typically a solid at room temperature and exhibits low solubility in water due to its hydrophobic nature. Its chemical stability is notable, although it can undergo reactions typical of aromatic amines, such as electrophilic substitution. The presence of fluorine atoms contributes to its unique reactivity and potential applications in materials science and medicinal chemistry. Safety precautions should be taken when handling this compound, as with many fluorinated organic substances, due to potential toxicity and environmental concerns.

Formula: C₆H₅BClFO₂

InChI: InChI=1/C6H5BClFO2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,10-11H

SMILES: c1c(cc(cc1Cl)F)B(O)O

Synonyms:

• 2,5-Bis(Trifluoromethyl)Benzenamine
• (3-Chloro-5-Fluorophenyl)Boronic Acid
• 2,5-Ditrifluoromethylaniline
• 2,5-Bis Trifluoromethyl aniline

2,5-Bis(trifluoromethyl)aniline, 99%

CAS: 328-93-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₅F₆N

Purity: 99%

Color and Shape: Liquid, Clear colorless to yellow to orange

Molecular weight: 229.13

Ref: 02-L14706

2,5-Bis(trifluoromethyl)aniline

CAS: 328-93-8

Formula: C₈H₅F₆N

Purity: 98%

Color and Shape: Liquid

Molecular weight: 229.1224

Ref: IN-DA003FW7

2,5-Bis(trifluoromethyl)aniline

CAS: 328-93-8

2,5-Bis(trifluoromethyl)aniline

Formula: C₈H₅F₆N

Purity: 98%

Color and Shape: clear. almost colourless liquid

Molecular weight: 229.12g/mol

Ref: 54-PC3058

2,5-Bis(trifluoromethyl)aniline

CAS: 328-93-8

Formula: C₈H₅F₆N

Purity: >98.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 229.13

Ref: 3B-B2544

2,5-Bis-(trifluoromethyl)aniline

CAS: 328-93-8

Formula: C₈H₅F₆N

Color and Shape: Neat

Molecular weight: 229.12

Ref: 86-MM1424.01

2,5-Bis-trifluoromethylaniline

CAS: 328-93-8

Formula: C₈H₅F₆N

Molecular weight: 229.13

Ref: 7W-GK4865

Dutasteride Impurity 24

CAS: 328-93-8

Formula: C₈H₅F₆N

Molecular weight: 229.13

Ref: 4Z-D-3544

2,5-Bis(trifluoromethyl)aniline

CAS: 328-93-8

Formula: C₈H₅F₆N

Purity: 97%

Color and Shape: Liquid

Molecular weight: 229.125

Ref: 10-F004996

2,5-Bis(trifluoromethyl)aniline

Controlled Product

CAS: 328-93-8

Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).
References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);

Formula: C₈H₅F₆N

Color and Shape: Colourless

Molecular weight: 229.12

Ref: TR-B585490

Dutasteride Impurity 3

CAS: 328-93-8

Formula: C₈H₅F₆N

Molecular weight: 229.1

Ref: ST-EA-CP-D30017