CAS 32808-51-8

Bucloxic acid

Description:

Bucloxic acid, with the CAS number 32808-51-8, is a chemical compound that belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing inflammation and pain. Bucloxic acid is typically used for its analgesic and anti-inflammatory properties in various medical applications. The compound is known for its moderate solubility in organic solvents and limited solubility in water, which can influence its bioavailability and pharmacokinetics. Its chemical structure features a carboxylic acid functional group, contributing to its acidic properties. As with many NSAIDs, potential side effects may include gastrointestinal discomfort and cardiovascular risks, necessitating careful consideration in therapeutic use. Overall, bucloxic acid exemplifies the characteristics of a typical NSAID, providing relief from pain and inflammation while requiring monitoring for adverse effects.

Formula: C₁₆H₁₉ClO₃

InChI: InChI=1S/C16H19ClO3/c17-14-10-12(15(18)8-9-16(19)20)6-7-13(14)11-4-2-1-3-5-11/h6-7,10-11H,1-5,8-9H2,(H,19,20)

InChI key: InChIKey=IJTPQQVCKPZIMV-UHFFFAOYSA-N

SMILES: ClC1=C(C=CC(C(CCC(O)=O)=O)=C1)C2CCCCC2

Synonyms:

• 3-(3-Chloro-4-cyclohexylbenzoyl)propionic acid
• 3-Chloro-4-cyclohexyl-alpha-oxobenzenebutanoic acid
• 3-Chloro-4-cyclohexyl-γ-oxobenzenebutanoic acid
• 4-(3-Chloro-4-Cyclohexylphenyl)-4-Oxobutanoic Acid
• 4-(3-Chloro-4-cyclohexylphenyl)-4-oxo-butyric acid
• 4-(4-Cyclohexyl-3-chlorophenyl)-4-oxobutyric acid
• 4-(m-Chloro-p-cyclohexylphenyl)-4-oxobutyric acid
• 804 Cb
• 804Cb
• Acide bucloxique
• Acide bucloxique [INN-French]
• Acido bucloxico
• Acido bucloxico [INN-Spanish]
• Acidum bucloxicum
• Acidum bucloxicum [INN-Latin]
• Benzenebutanoic acid, 3-chloro-4-cyclohexyl-alpha-oxo-
• Benzenebutanoic acid, 3-chloro-4-cyclohexyl-γ-oxo-
• Brn 2949306
• Bucloxic acid [INN:DCF]
• Bucloxinsaeure
• Bucloxinsaeure [German]
• Bucloxonic acid
• Esfar
• Propionic acid, 3-(3-chloro-4-cyclohexylbenzoyl)-
• Unii-Kv89R7Elf8
• l'Acide bucloxique
• l'Acide bucloxique [French]

Bucloxic acid

CAS: 32808-51-8

Bucloxic acid is a novel amide compound that has been shown to have synergistic activity with chemokines. It has been used in animal studies to reduce bowel disease caused by inflammatory bowel disease, and is currently undergoing toxicological studies. Bucloxic acid may be useful as an anti-inflammatory agent in the treatment of autoimmune diseases and metabolic disorders. In addition, bucloxic acid has been shown to have significant inhibitory effects on choroidal neovascularization (CNV) in mice models of age-related macular degeneration (AMD).

Formula: C₁₆H₁₉ClO₃

Purity: Min. 95%

Molecular weight: 294.77 g/mol

Ref: 3D-HBA80851

Bucloxic acid

CAS: 32808-51-8

Bucloxic acid is an anti-inflammatory pyrazole derivative used in the treatment of chronic glomerular nephropathies.

Formula: C₁₆H₁₉ClO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 294.77

Ref: TM-T14836