CAS 328565-16-8

Formula: C14H11NO4

InChI: InChI=1S/C14H11NO4/c16-9-12-7-11(6-10-4-2-1-3-5-10)8-13(14(12)17)15(18)19/h1-5,7-9,17H,6H2

InChI key: RKJXVCLOGNLZOI-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)CC2=CC(=C(C(=C2)[N+](=O)[O-])O)C=O

Col003

CAS: 328565-16-8

Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).

Formula: C₁₄H₁₁NO₄

Purity: 99.03% - 99.96%

Color and Shape: Solid

Molecular weight: 257.2414

Ref: TM-T10860

Col003

CAS: 328565-16-8

Formula: C₁₄H₁₁NO₄

Purity: 99.96%

Molecular weight: 257.2414

Ref: IN-DA00JJCH

5-Benzyl-2-Hydroxy-3-Nitrobenzaldehyde

CAS: 328565-16-8

5-Benzyl-2-Hydroxy-3-Nitrobenzaldehyde

Formula: C₁₄H₁₁NO₄

Purity: 98%

Molecular weight: 257.24

Ref: 54-OR1023100

Col003

CAS: 328565-16-8

Col003

Formula: C₁₄H₁₁NO₄

Purity: ≥98%

Molecular weight: 257.24

Ref: 54-BUP15354

Col003

CAS: 328565-16-8

Col003 is a small molecule that was designed to bind competitively to the human immunodeficient virus (HIV) protein, gp120. It is also a chaperone molecule that can be used for the treatment of HIV/AIDS and cancer. Col003 binds to a specific region of gp120 called the CD4 binding site and prevents gp120 from binding to CD4 receptors on cells. This prevents HIV from entering into the cell and spreading infection. Col003 has also been shown to inhibit viral replication by interfering with viral DNA synthesis in human cells infected with HIV-1 or HIV-2. The structure of Col003 was derived from Brassica oleracea proteins, particularly its sequence similarity with Collagen I.

Formula: C₁₄H₁₁NO₄

Purity: Min. 95%

Molecular weight: 257.24 g/mol

Ref: 3D-DNA56516