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CAS 32886-40-1

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Boc-Glu(OBzl)-OSu

Description:
Boc-Glu(OBzl)-OSu, also known as N-Boc-L-glutamic acid benzyl ester N-hydroxysuccinimide ester, is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a Boc (tert-butyloxycarbonyl) protecting group, which is often employed to protect amino groups during chemical reactions. The glutamic acid moiety provides a carboxylic acid functional group, while the benzyl ester enhances the lipophilicity and stability of the compound. The presence of the N-hydroxysuccinimide (OSu) group facilitates the formation of stable amide bonds with nucleophiles, making it useful for coupling reactions in peptide synthesis. This compound is typically a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. Its reactivity and functional groups make it valuable in the development of peptide-based therapeutics and in various biochemical applications. Proper handling and storage conditions are essential to maintain its stability and reactivity.
Formula:C21H26N2O8
InChI:InChI=1/C21H26N2O8/c1-21(2,3)30-20(28)22-15(19(27)31-23-16(24)10-11-17(23)25)9-12-18(26)29-13-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,22,28)
SMILES:CC(C)(C)OC(=NC(CCC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O)O
Synonyms:
  • 5-benzyl 1-(2,5-dioxopyrrolidin-1-yl) N-(tert-butoxycarbonyl)glutamate
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