CAS 328944-75-8

L-Isoleucine,L-tyrosyl-L-asparaginyl-L-valyl-L-tyrosylglycyl-L-isoleucyl-L-a-glutamyl-L-seryl-L-valyl-L-lysyl-(9CI)

Description:

L-Isoleucine, L-tyrosyl-L-asparaginyl-L-valyl-L-tyrosylglycyl-L-isoleucyl-L-α-glutamyl-L-seryl-L-valyl-L-lysyl (9CI) is a complex peptide composed of multiple amino acids, reflecting a specific sequence that contributes to its unique properties. As a peptide, it exhibits characteristics typical of proteins, including solubility in water, the ability to form hydrogen bonds, and potential biological activity. The presence of various amino acid side chains, such as isoleucine, tyrosine, asparagine, valine, glycine, glutamic acid, serine, and lysine, imparts diverse functional properties, including hydrophobic and hydrophilic interactions, which can influence its conformation and stability. This compound may play a role in biological processes, potentially acting as a signaling molecule or participating in metabolic pathways. Its CAS number, 328944-75-8, allows for precise identification in chemical databases. Overall, the characteristics of this peptide suggest it may have applications in biochemistry, pharmacology, or nutrition, although specific functional studies would be necessary to elucidate its exact roles and potential uses.

Formula: C₆₀H₉₃N₁₃O₁₈

Synonyms:

• Pep2-Svki

pep2-SVKI

CAS: 328944-75-8

Inhibitor peptide from GluA2's C-terminus blocks its PDZ interactions, enhancing AMPA currents and inhibiting LTD.

Formula: C₆₀H₉₃N₁₃O₁₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 1284.47

Ref: TM-TP1944

pep2-SVKI

CAS: 328944-75-8

Pep2 is a potent, selective, and orally active positive allosteric modulator of the AMPA receptor. It binds to the GluR2 subunit at the synapse and increases the probability of glutamate release. Pep2-SVKI is a modified form of the peptide that has been shown to have potentiating effects on retinal ganglion cells in vitro. Pep2-SVKI is also able to induce depression in postsynaptic neurons by increasing potassium channel activity and reducing neurotransmitter release. The precise mechanism by which pep2-SVKI induces depression is not yet known, but it may be due to its ability to interact with cytosolic proteins or its potential interaction with cellular signaling pathways in neurons.

Formula: C₆₀H₉₃N₁₃O₁₈

Purity: Min. 95%

Molecular weight: 1,284.5 g/mol

Ref: 3D-DNA94475