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CAS 328955-61-9

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6-bromo-4-(trifluoromethyl)quinolin-2(1H)-one

Description:
6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one is a synthetic organic compound characterized by its quinoline structure, which is a bicyclic aromatic compound containing a nitrogen atom. The presence of a bromine atom at the 6-position and a trifluoromethyl group at the 4-position significantly influences its chemical properties, including its reactivity and solubility. This compound typically exhibits a pale yellow to off-white crystalline appearance. It is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity. The trifluoromethyl group enhances lipophilicity, which can improve the compound's ability to penetrate biological membranes. Additionally, the nitrogen atom in the quinoline ring can participate in hydrogen bonding, affecting its interaction with biological targets. As with many halogenated compounds, it is important to handle this substance with care due to potential toxicity and environmental impact. Proper safety measures should be observed when working with this compound in laboratory settings.
Formula:C10H5BrF3NO
InChI:InChI=1S/C10H5BrF3NO/c11-5-1-2-8-6(3-5)7(10(12,13)14)4-9(16)15-8/h1-4H,(H,15,16)
SMILES:c1cc2c(cc1Br)c(cc(n2)O)C(F)(F)F
Synonyms:
  • 2(1H)-Quinolinone, 6-bromo-4-(trifluoromethyl)-
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