CAS 328968-36-1

4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid

Description:

The chemical substance known as 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid, with the CAS number 328968-36-1, is a complex organic compound characterized by its multi-functional structure. It features a benzoic acid moiety, which contributes to its acidic properties, and a pyrazole ring that is known for its biological activity. The presence of a furan ring and a nitrophenyl group indicates potential for diverse chemical reactivity and interactions. The compound's structure suggests it may exhibit significant pharmacological properties, possibly acting as an intermediate in drug synthesis or as a bioactive molecule. Its solubility, stability, and reactivity would depend on the specific functional groups and their arrangement, influencing its potential applications in medicinal chemistry or material science. As with many organic compounds, safety and handling precautions are essential due to the presence of nitro groups, which can be sensitive and potentially hazardous.

Formula: C₂₄H₁₉N₃O₆

InChI: InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)

InChI key: InChIKey=HEKJYZZSCQBJGB-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(C=C(C)C(C)=C1)C=2OC(C=C3C(=O)N(N=C3C)C4=CC=C(C(O)=O)C=C4)=CC2

Synonyms:

• Benzoic acid, 4-[4-[[5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-
• C 646
• 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
• (Z)-4-(4-((5-(4,5-diMethyl-2-nitrophenyl)furan-2-yl)Methylene)-3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
• 104475
• Histone Acetyltransferase p300 Inhibitor, C646 - Calbiochem
• 4-[(4Z)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid
• (E)-4-(4-((5-(4,5-diMethyl-2-nitrophenyl)furan-2-yl)Methylene)-3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
• C646, p300/CBP Inhibitor
• C 646 USP/EP/BP
• 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid C646
• C 646 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-benzoic acid
• C646 C-646 C 646
• C647
• C-646;C 646
• CS-1006
• 4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyraz

C 646

CAS: 328968-36-1

Formula: C₂₄H₁₉N₃O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 445.4242

Ref: IN-DA00C6F4

C 646

CAS: 328968-36-1

C 646

Purity: 98%

Molecular weight: 445.42g/mol

Ref: 54-OR1026328

C646

CAS: 328968-36-1

C646

Purity: ≥95%

Molecular weight: 445.42g/mol

Ref: 54-BUP12958

C646

CAS: 328968-36-1

C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).

Formula: C₂₄H₁₉N₃O₆

Purity: 98% - 99.21%

Color and Shape: Solid

Molecular weight: 445.42

Ref: TM-T2452

C646

CAS: 328968-36-1

Formula: C₂₄H₁₉N₃O₆

Molecular weight: 445.4

Ref: 7W-GL5672

Histone Acetyltransferase p300 Inhibitor, C646

CAS: 328968-36-1

Histone Acetyltransferase p300 Inhibitor, C646 (C646) is a small molecule that inhibits the activity of Histone Acetyltransferase p300. Histone Acetyltransferase p300 is a protein that acetylates histones, which modifies the chromatin structure and affects gene expression. C646 can bind to Histone Acetyltransferase p300 and inhibit its activity, leading to a decrease in gene expression. C646 has been shown to be effective against cancer cells in multiple cell lines and has been shown to induce apoptosis in human leukemia cells. It also induces cellular senescence and growth arrest in some cell lines.

Formula: C₂₄H₁₉N₃O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 445.42 g/mol

Ref: 3D-DNA96836