CAS 330-12-1

4-(Trifluoromethoxy)benzoic acid

Description:

4-(Trifluoromethoxy)benzoic acid, with the CAS number 330-12-1, is an aromatic carboxylic acid characterized by the presence of a trifluoromethoxy group (-O-CF3) attached to the para position of a benzoic acid structure. This compound typically appears as a white to off-white solid and is known for its relatively high melting point. The trifluoromethoxy group imparts unique electronic properties, enhancing the compound's acidity and influencing its reactivity. It is soluble in organic solvents such as ethanol and acetone but has limited solubility in water due to its hydrophobic characteristics. This compound is often utilized in organic synthesis and pharmaceutical research, particularly in the development of fluorinated compounds, which can exhibit improved biological activity. Additionally, its unique structure makes it a valuable intermediate in the synthesis of various agrochemicals and materials science applications. Safety precautions should be taken when handling this substance, as it may pose health risks if ingested or inhaled.

Formula: C₈H₅F₃O₃

InChI: InChI=1S/C8H5F3O3/c9-8(10,11)14-6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)

InChI key: InChIKey=RATSANVPHHXDCT-UHFFFAOYSA-N

SMILES: O(C(F)(F)F)C1=CC=C(C(O)=O)C=C1

Synonyms:

• 4-(Trifluoromethoxy)Benzoate
• 4-[(Trifluormethyl)sulfanyl]benzolcarbonylchlorid
• 4-[(Trifluoromethyl)sulfanyl]benzoyl chloride
• Benzoic acid, 4-(trifluoromethoxy)-
• Benzoyl chloride, 4-[(trifluoromethyl)thio]-
• p-(Trifluoromethoxy)benzoic acid
• p-Anisic acid, α,α,α-trifluoro-
• p-Trifluoromethoxybenzoic acid
• 4-(Trifluoromethoxy)benzoic acid
• 4-(Trifluoromethyloxy)benzoic acid

4-(Trifluoromethoxy)benzoic acid

CAS: 330-12-1

Formula: C₈H₅F₃O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 206.1187

Ref: IN-DA003KAZ

4-(Trifluoromethoxy)benzoic acid

CAS: 330-12-1

4-(Trifluoromethoxy)benzoic acid

Formula: C₈H₅F₃O₃

Purity: 97%

Color and Shape: white to off-white powder

Molecular weight: 206.12g/mol

Ref: 54-PC7438

4-TrifluoromethoxybenzoicAcid-α-13C

CAS: 330-12-1

Formula: CF₃OC₆H₄₁₃COOH

Purity: 99 atom % 13C

Color and Shape: White Solid

Molecular weight: 618.21952

Ref: 3U-C6204

4-(Trifluoromethoxy)benzoic Acid

CAS: 330-12-1

Formula: C₈H₅F₃O₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 206.12

Ref: 3B-T1400

4-(Trifluoromethoxy)benzoic acid

CAS: 330-12-1

Formula: C₈H₅F₃O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 206.12

Ref: 10-F001545

4-(Trifluoromethoxy)benzoic Acid

Controlled Product

CAS: 330-12-1

Applications 4-(Trifluoromethoxy)benzoic Acid is a substituted benzoic acid used in the preparation of a various biologically active compounds such as antifungal and antimalarial agents.
References Jiang, Y. et al.: Bioorg. Med. Chem. Lett., 21, 4471 (2011); Herrin, T.R. et al.: J. Med. Chem., 18, 1216 (1975);

Formula: C₈H₅F₃O₃

Color and Shape: Neat

Molecular weight: 206.12

Ref: TR-T790720