CAS 33016-12-5

(3E)-5-benzyl-3-[1-(phenylamino)ethylidene]pyrrolidine-2,4-dione

Description:

(3E)-5-benzyl-3-[1-(phenylamino)ethylidene]pyrrolidine-2,4-dione, with the CAS number 33016-12-5, is a synthetic organic compound characterized by its complex structure, which includes a pyrrolidine ring and multiple functional groups. This compound features a benzyl group and a phenylamino substituent, contributing to its potential biological activity. The presence of the dione functional groups indicates that it may participate in various chemical reactions, such as nucleophilic additions or condensation reactions. Its stereochemistry, denoted by the (3E) configuration, suggests specific spatial arrangements that can influence its reactivity and interactions with biological targets. Compounds of this nature are often studied for their pharmacological properties, including potential anti-cancer or anti-inflammatory effects. The solubility, stability, and reactivity of this compound can vary based on environmental conditions, such as pH and temperature, making it a subject of interest in medicinal chemistry and drug development. Further research is necessary to fully elucidate its properties and potential applications.

Formula: C₁₉H₁₈N₂O₂

InChI: InChI=1/C19H18N2O2/c1-13(20-15-10-6-3-7-11-15)17-18(22)16(21-19(17)23)12-14-8-4-2-5-9-14/h2-11,16,20H,12H2,1H3,(H,21,23)/b17-13+

Synonyms:

• 2,4-Pyrrolidinedione, 3- (1-anilinoethylidene)-5-benzyl-
• 2,4-Pyrrolidinedione, 3-(1-(phenylamino)ethylidene)-5-(phenylmethyl)-

TN-16

CAS: 33016-12-5

Formula: C₁₉H₁₈N₂O₂

Purity: 98%

Molecular weight: 306.3584

Ref: IN-DA00C0KL

TN-16

CAS: 33016-12-5

TN-16

Purity: ≥98%

Molecular weight: 306.36g/mol

Ref: 54-BUP09803

TN-16

CAS: 33016-12-5

Formula: C₁₉H₁₈N₂O₂

Molecular weight: 306.36

Ref: 7W-GL9486

TN-16

CAS: 33016-12-5

Formula: C₁₉H₁₈N₂O₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 306.37

Ref: 3B-T3877

TN-16

CAS: 33016-12-5

TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)

Formula: C₁₉H₁₈N₂O₂

Purity: 99.54%

Color and Shape: Solid

Molecular weight: 306.36

Ref: TM-T7800

TN-16

CAS: 33016-12-5

TN-16 is a synthetic taxane with a high affinity for the microtubule polymerization protein, taxol. It binds to the β-taxol and prevents it from binding to the ɣ-taxol, which disrupts the formation of the polymerized microtubules. TN-16 is also reversible, meaning that it can be displaced by nocodazole or podophyllotoxin. In addition, TN-16 has been shown to inhibit cell proliferation in ovary cells and metaphase chromosomes in cell culture experiments. This drug also has shown anti-tumor activity in mice when used in combination with vinblastine or daunorubicin. TN-16 has cross resistance with other drugs such as vinca alkaloids, which are plant alkaloids that have been used to treat various cancers since they were first isolated from plants in Madagascar in 1939.

Formula: C₁₉H₁₈N₂O₂

Purity: Min. 95%

Molecular weight: 306.36 g/mol

Ref: 3D-IBA01612