6-Chloro-2-mercaptoquinazolin-4(3H)-one is a heterocyclic compound characterized by its quinazoline core, which is a bicyclic structure containing both benzene and pyrimidine rings. The presence of a chlorine atom at the 6-position and a thiol (-SH) group at the 2-position contributes to its unique chemical properties. This compound typically exhibits moderate solubility in polar solvents due to the presence of the mercapto group, which can engage in hydrogen bonding. It may also display biological activity, making it of interest in pharmaceutical research, particularly in the development of potential therapeutic agents. The compound's structure allows for various chemical modifications, which can enhance its efficacy or alter its pharmacokinetic properties. Additionally, it may participate in various chemical reactions, such as nucleophilic substitutions or oxidation, due to the reactive thiol group. Overall, 6-chloro-2-mercaptoquinazolin-4(3H)-one is a versatile compound with potential applications in medicinal chemistry and related fields.

6-chloro-2-mercaptoquinazolin-4(3H)-one

33017-85-5: 6-Chloro-2-mercaptoquinazolin-4(3H)-one is a heterocyclic compound characterized by its quinazoline core, which is a bicyclic structure containing both benzene and pyrimidine rings. The presence of a chlorine atom at the 6-position and a thiol (-SH) group at the 2-position contributes to its unique chemical properties. This compound typically exhibits moderate solubility in polar solvents due to the presence of the mercapto group, which can engage in hydrogen bonding. It may also display biological activity, making it of interest in pharmaceutical research, particularly in the development of potential therapeutic agents. The compound's structure allows for various chemical modifications, which can enhance its efficacy or alter its pharmacokinetic properties. Additionally, it may participate in various chemical reactions, such as nucleophilic substitutions or oxidation, due to the reactive thiol group. Overall, 6-chloro-2-mercaptoquinazolin-4(3H)-one is a versatile compound with potential applications in medicinal chemistry and related fields.

<p>SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase (SMase) inhibitor with an IC50 value of 6.43 µM against Bacillus cereus SMase. It also inhibits eqBuChE with an inhibition rate of 59.50% at a concentration of 50 µM. SMase-IN-1 forms a complex with Cu2+ through bio-metal interactions and can inhibit hemolysis of sheep red blood cells induced by Bacillus cereus.</p>

CAS 33017-85-5

6-chloro-2-mercaptoquinazolin-4(3H)-one

SMase-IN-1

Ref: TM-T204131